[破伤风,一种在洛美(多哥)仍然流行的传染病]。

Medecine tropicale et sante internationale Pub Date : 2023-09-24 eCollection Date: 2023-09-30 DOI:10.48327/mtsi.v3i3.2023.273
Lidaw Déassoua Bawe, Awèréou Kotosso, Akouda Akessiwe Patassi, Bawoubadi Abaltou, Olivier Pabamé Naora, Abdou-Razak Moukaïla, Ohouzangbe Doulé, Majesté Ihou Watéba
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引用次数: 0

摘要

导言:尽管存在扩大免疫计划,破伤风仍然是多哥的一个公共卫生问题:2008年1月1日至2018年12月31日,多哥洛美Sylvanus Olympio教学医院传染病和热带病科对破伤风病例进行了一项回顾性和描述性队列研究:我们共收治了208例破伤风病例,占该医院传染病和热带病科全部住院病例的6.5%。患者年龄中位数为 23 [13-38 岁],男性占多数(81.2%)。患者为工人(63.5%),主要来自城市地区(65.9%)。只有 9.3% 的患者接种过破伤风疫苗。门诊病人以皮肤伤口为主(66.8%)。191名患者(91.8%)主要通过鞘内途径(189名患者(91.1%))注射了抗破伤风血清。并发症主要是伤口感染(8 例)、脓毒性休克(3 例)、急性呼吸衰竭和皮肤坏死(1 例)。致死率为 27.4%:结论:破伤风的发病率,尤其是青少年发病率仍然很高,致死率也很高。结论:破伤风的发病率,尤其是青少年发病率仍然很高,而且致死率很高。因此,必须特别强调疫苗强化接种的重要性。
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[Tetanus, an infectious disease still topical in Lome (Togo)].

Introduction: Tetanus still remains a public health problem in Togo despite the existence of the Expanded Program on Immunization.

Patients and method: A retrospective and descriptive cohort study was performed from January 1, 2008 to December 31, 2018 in the infectious and tropical diseases department of Sylvanus Olympio teaching hospital of Lome (Togo) on tetanus cases.

Results: We included 208 tetanus cases accounting for 6.5% of the whole hospitalizations in the infectious and tropical diseases department at this hospital. The median age of the patients was 23 [13-38 years] with male predominance (81.2%). The patients were workers (63.5%) and came mainly from urban areas (65.9%). Tetanus vaccination was only up to date in 9.3% of patients. Gateways were dominated by skin wounds (66.8%). Antitetanus serum was administered in 191 patients (91.8%) mainly through intrathecal route (189 patients (91.1%)). Complications were marked by superinfection of the wound (n=8), septic shock (n=3), acute respiratory failure and skin necrosis in 1 case respectively. The lethality was 27.4%.

Conclusion: The morbidity of tetanus, in particular juvenile morbidity, remains high with significant lethality. It is therefore important to place particular emphasis on the vaccine booster component.

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