{"title":"血浆活化水对延长 COVID-19 患者病毒脱落期的安全性和有效性:随机对照试验","authors":"Xiaoya Guo, Xing Lv, Yunfu Wu, Mingming Wang, Shuo Wu, Li Guo, Zifeng Wang, Zhihong Shi, Rui Huang, Hua Zhang, Xiaona Niu, Mingzhe Rong, Liqiang Song, Dingxin Liu","doi":"10.1002/ppap.202300195","DOIUrl":null,"url":null,"abstract":"Shortening the duration of the viral shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical to controlling viral transmission, alleviating the burden on the healthcare system, and ultimately mitigating the impact of the pandemic. This randomized, single-blind, placebo-controlled clinical trial aimed to investigate the safety and efficacy of gargling with plasma-activated water (PAW) on prolonged viral shedding in patients infected with SARS-CoV-2 Delta and Omicron variants. Sixty-two subjects, aged 18–80 years and infected with SARS-CoV-2, were recruited at two coronavirus disease 2019 (COVID-19)-designated hospitals in Shaanxi from January to March 2022. Primary outcomes included cumulative conversion rates, incidence of adverse reactions, and biosafety parameters. Results suggested that PAW gargling treatment might contribute to reducing the duration of SARS-CoV-2 Delta and Omicron variant infections and alleviating symptoms.","PeriodicalId":20135,"journal":{"name":"Plasma Processes and Polymers","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Safety and efficacy of plasma-activated water on prolonged viral shedding of COVID-19 patients: A randomized controlled trial\",\"authors\":\"Xiaoya Guo, Xing Lv, Yunfu Wu, Mingming Wang, Shuo Wu, Li Guo, Zifeng Wang, Zhihong Shi, Rui Huang, Hua Zhang, Xiaona Niu, Mingzhe Rong, Liqiang Song, Dingxin Liu\",\"doi\":\"10.1002/ppap.202300195\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Shortening the duration of the viral shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical to controlling viral transmission, alleviating the burden on the healthcare system, and ultimately mitigating the impact of the pandemic. This randomized, single-blind, placebo-controlled clinical trial aimed to investigate the safety and efficacy of gargling with plasma-activated water (PAW) on prolonged viral shedding in patients infected with SARS-CoV-2 Delta and Omicron variants. Sixty-two subjects, aged 18–80 years and infected with SARS-CoV-2, were recruited at two coronavirus disease 2019 (COVID-19)-designated hospitals in Shaanxi from January to March 2022. Primary outcomes included cumulative conversion rates, incidence of adverse reactions, and biosafety parameters. Results suggested that PAW gargling treatment might contribute to reducing the duration of SARS-CoV-2 Delta and Omicron variant infections and alleviating symptoms.\",\"PeriodicalId\":20135,\"journal\":{\"name\":\"Plasma Processes and Polymers\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2023-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Plasma Processes and Polymers\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1002/ppap.202300195\",\"RegionNum\":3,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasma Processes and Polymers","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1002/ppap.202300195","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSICS, APPLIED","Score":null,"Total":0}
Safety and efficacy of plasma-activated water on prolonged viral shedding of COVID-19 patients: A randomized controlled trial
Shortening the duration of the viral shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical to controlling viral transmission, alleviating the burden on the healthcare system, and ultimately mitigating the impact of the pandemic. This randomized, single-blind, placebo-controlled clinical trial aimed to investigate the safety and efficacy of gargling with plasma-activated water (PAW) on prolonged viral shedding in patients infected with SARS-CoV-2 Delta and Omicron variants. Sixty-two subjects, aged 18–80 years and infected with SARS-CoV-2, were recruited at two coronavirus disease 2019 (COVID-19)-designated hospitals in Shaanxi from January to March 2022. Primary outcomes included cumulative conversion rates, incidence of adverse reactions, and biosafety parameters. Results suggested that PAW gargling treatment might contribute to reducing the duration of SARS-CoV-2 Delta and Omicron variant infections and alleviating symptoms.
期刊介绍:
Plasma Processes & Polymers focuses on the interdisciplinary field of low temperature plasma science, covering both experimental and theoretical aspects of fundamental and applied research in materials science, physics, chemistry and engineering in the area of plasma sources and plasma-based treatments.