老龄化与疾病风险因素:了解过去疾病的古流行病学新方法

IF 1.3 3区 地球科学 Q3 PALEONTOLOGY International Journal of Paleopathology Pub Date : 2023-12-21 DOI:10.1016/j.ijpp.2023.11.004
Jo Appleby
{"title":"老龄化与疾病风险因素:了解过去疾病的古流行病学新方法","authors":"Jo Appleby","doi":"10.1016/j.ijpp.2023.11.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>To outline a methodology that enables the reconstruction of age-related disease risk in past societies.</p></div><div><h3>Materials</h3><p>Modern epidemiological evidence considering risk factors for age-related disease is combined with contextual information about an archaeological society of interest.</p></div><div><h3>Methods</h3><p>Data gathered is used to create a qualitative population-specific risk model for the disease of interest. To provide a case study, a risk model is constructed for Chronic Obstructive Pulmonary Disease (COPD) in the Eastern English Bronze Age.</p></div><div><h3>Results</h3><p>This enables the first rigorous approach to reconstructing age-related disease risk in the past. A risk model shows a high degree of COPD risk in the Eastern English Bronze Age, with a major contribution from indoor airborne pollution and agricultural practices.</p></div><div><h3>Significance</h3><p>This represents a significant new approach in human paleopathology, facilitating understanding of the occurrence of a wide variety of diseases in the past, without the need for well-preserved skeletons of identified elderly individuals.</p></div><div><h3>Limitations</h3><p>The risk models generated are, of necessity, qualitative rather than quantitative, since we are unable to calculate the size of risk factors in the past with certainty.</p></div><div><h3>Suggestions for further research</h3><p>The methodology could be applied to a wide variety of diseases and for many past societies.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1879981723000736/pdfft?md5=09b247a4e02d8c623ef30e422a6cb7df&pid=1-s2.0-S1879981723000736-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Ageing and disease risk factors: A new paleoepidemiological methodology for understanding disease in the past\",\"authors\":\"Jo Appleby\",\"doi\":\"10.1016/j.ijpp.2023.11.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>To outline a methodology that enables the reconstruction of age-related disease risk in past societies.</p></div><div><h3>Materials</h3><p>Modern epidemiological evidence considering risk factors for age-related disease is combined with contextual information about an archaeological society of interest.</p></div><div><h3>Methods</h3><p>Data gathered is used to create a qualitative population-specific risk model for the disease of interest. To provide a case study, a risk model is constructed for Chronic Obstructive Pulmonary Disease (COPD) in the Eastern English Bronze Age.</p></div><div><h3>Results</h3><p>This enables the first rigorous approach to reconstructing age-related disease risk in the past. A risk model shows a high degree of COPD risk in the Eastern English Bronze Age, with a major contribution from indoor airborne pollution and agricultural practices.</p></div><div><h3>Significance</h3><p>This represents a significant new approach in human paleopathology, facilitating understanding of the occurrence of a wide variety of diseases in the past, without the need for well-preserved skeletons of identified elderly individuals.</p></div><div><h3>Limitations</h3><p>The risk models generated are, of necessity, qualitative rather than quantitative, since we are unable to calculate the size of risk factors in the past with certainty.</p></div><div><h3>Suggestions for further research</h3><p>The methodology could be applied to a wide variety of diseases and for many past societies.</p></div>\",\"PeriodicalId\":48817,\"journal\":{\"name\":\"International Journal of Paleopathology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2023-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1879981723000736/pdfft?md5=09b247a4e02d8c623ef30e422a6cb7df&pid=1-s2.0-S1879981723000736-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Paleopathology\",\"FirstCategoryId\":\"89\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1879981723000736\",\"RegionNum\":3,\"RegionCategory\":\"地球科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PALEONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Paleopathology","FirstCategoryId":"89","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1879981723000736","RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PALEONTOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

材料将考虑老年疾病风险因素的现代流行病学证据与相关考古社会的背景信息相结合。方法利用收集到的数据为相关疾病建立一个定性的特定人群风险模型。为了提供一个案例研究,我们为英格兰东部青铜时代的慢性阻塞性肺病(COPD)构建了一个风险模型。风险模型显示,英格兰东部青铜时代的慢性阻塞性肺病风险很高,室内空气污染和农业生产方式是主要原因。意义这代表了人类古病理学的一种重要新方法,有助于了解过去各种疾病的发生情况,而不需要保存完好的已确认老人的骨骼。局限性由于我们无法准确计算过去风险因素的大小,因此所生成的风险模型必然是定性而非定量的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Ageing and disease risk factors: A new paleoepidemiological methodology for understanding disease in the past

Objectives

To outline a methodology that enables the reconstruction of age-related disease risk in past societies.

Materials

Modern epidemiological evidence considering risk factors for age-related disease is combined with contextual information about an archaeological society of interest.

Methods

Data gathered is used to create a qualitative population-specific risk model for the disease of interest. To provide a case study, a risk model is constructed for Chronic Obstructive Pulmonary Disease (COPD) in the Eastern English Bronze Age.

Results

This enables the first rigorous approach to reconstructing age-related disease risk in the past. A risk model shows a high degree of COPD risk in the Eastern English Bronze Age, with a major contribution from indoor airborne pollution and agricultural practices.

Significance

This represents a significant new approach in human paleopathology, facilitating understanding of the occurrence of a wide variety of diseases in the past, without the need for well-preserved skeletons of identified elderly individuals.

Limitations

The risk models generated are, of necessity, qualitative rather than quantitative, since we are unable to calculate the size of risk factors in the past with certainty.

Suggestions for further research

The methodology could be applied to a wide variety of diseases and for many past societies.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.90
自引率
25.00%
发文量
43
期刊介绍: Paleopathology is the study and application of methods and techniques for investigating diseases and related conditions from skeletal and soft tissue remains. The International Journal of Paleopathology (IJPP) will publish original and significant articles on human and animal (including hominids) disease, based upon the study of physical remains, including osseous, dental, and preserved soft tissues at a range of methodological levels, from direct observation to molecular, chemical, histological and radiographic analysis. Discussion of ways in which these methods can be applied to the reconstruction of health, disease and life histories in the past is central to the discipline, so the journal would also encourage papers covering interpretive and theoretical issues, and those that place the study of disease at the centre of a bioarchaeological or biocultural approach. Papers dealing with historical evidence relating to disease in the past (rather than history of medicine) will also be published. The journal will also accept significant studies that applied previously developed techniques to new materials, setting the research in the context of current debates on past human and animal health.
期刊最新文献
Expanding the diagnostic scope of paleopathology: Identification of Q fever (Coxiella burnetii) using a One Paleopathology approach Rickets, resorption and revolution: An investigation into the relationship between vitamin D deficiency in childhood and osteoporosis in adulthood in an 18th-19th century population Characteristics of dental malocclusion in a 18th/19th century population from Radom (Poland) A severe case of bilateral humerus varus deformity from the Middle Bronze age necropolis of Olmo di Nogara, Northeast Italy. The contribution of biomechanical analysis to paleopathological study ABSTRACTS
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1