{"title":"迂回诊断纹身过敏？","authors":"Steffen Schubert, Carina Wolf, Ines Schreiver, Katherina Siewert, Uwe Karst","doi":"10.1007/s40629-023-00280-7","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Decorative tattoos and permanent make-up have been gaining popularity for years. Increasingly, intolerance reactions occur.</p><h3>Methods</h3><p>Literature search of PubMed and reference books on diagnostic and treatment options for tattoo complications.</p><h3>Results</h3><p>At least one third of persistent intolerance reactions to tattoos are allergic reactions. The diagnostic work-up should include the tattoo ink used and, particularly in cases of scattered eczema, other products applied. Pigments penetrate very poorly into the epidermis and are not available as commercial test preparations. Consequently, patch tests very often show (false) negative results in affected individuals. Allergological individual diagnosis and assessment of clinical relevance are rarely possible as the chemical composition of the culprit tattoo ink is usually unknown.</p><h3>Discussion</h3><p>Diagnosis of tattoo allergy is challenging. The IVDK Tattoo Study 2.0 enables the identification of metals and pigments in skin samples, the preparation of individual patch test preparations with pigments, and the investigation of specific T lymphocytes in blood samples. In addition, assessment of the clinical relevance can be improved by exposure data and results of laboratory diagnostics.</p></div>","PeriodicalId":37457,"journal":{"name":"Allergo Journal International","volume":"33 2","pages":"60 - 66"},"PeriodicalIF":0.0000,"publicationDate":"2023-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Tattoo allergy—diagnosis on a circuitous route?\",\"authors\":\"Steffen Schubert, Carina Wolf, Ines Schreiver, Katherina Siewert, Uwe Karst\",\"doi\":\"10.1007/s40629-023-00280-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Decorative tattoos and permanent make-up have been gaining popularity for years. Increasingly, intolerance reactions occur.</p><h3>Methods</h3><p>Literature search of PubMed and reference books on diagnostic and treatment options for tattoo complications.</p><h3>Results</h3><p>At least one third of persistent intolerance reactions to tattoos are allergic reactions. The diagnostic work-up should include the tattoo ink used and, particularly in cases of scattered eczema, other products applied. Pigments penetrate very poorly into the epidermis and are not available as commercial test preparations. Consequently, patch tests very often show (false) negative results in affected individuals. Allergological individual diagnosis and assessment of clinical relevance are rarely possible as the chemical composition of the culprit tattoo ink is usually unknown.</p><h3>Discussion</h3><p>Diagnosis of tattoo allergy is challenging. The IVDK Tattoo Study 2.0 enables the identification of metals and pigments in skin samples, the preparation of individual patch test preparations with pigments, and the investigation of specific T lymphocytes in blood samples. In addition, assessment of the clinical relevance can be improved by exposure data and results of laboratory diagnostics.</p></div>\",\"PeriodicalId\":37457,\"journal\":{\"name\":\"Allergo Journal International\",\"volume\":\"33 2\",\"pages\":\"60 - 66\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Allergo Journal International\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s40629-023-00280-7\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Allergo Journal International","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1007/s40629-023-00280-7","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景多年来，装饰性纹身和永久化妆越来越受欢迎。方法对有关纹身并发症的诊断和治疗方案的 PubMed 和参考书进行文献检索。结果至少有三分之一的持续性纹身不耐受反应是过敏反应。诊断工作应包括所使用的纹身墨水，尤其是在散在湿疹病例中，还应包括所使用的其他产品。颜料很难渗透到表皮中，也没有商业测试制剂。因此，斑贴试验在患者身上经常出现（假性）阴性结果。由于罪魁祸首纹身墨水的化学成分通常是未知的，因此很少有可能进行过敏学个体诊断和临床相关性评估。IVDK 纹身研究 2.0 可以鉴定皮肤样本中的金属和颜料，制备含有颜料的个体斑贴试验制剂，以及调查血液样本中的特异性 T 淋巴细胞。此外，暴露数据和实验室诊断结果还能改善临床相关性评估。
Decorative tattoos and permanent make-up have been gaining popularity for years. Increasingly, intolerance reactions occur.
Methods
Literature search of PubMed and reference books on diagnostic and treatment options for tattoo complications.
Results
At least one third of persistent intolerance reactions to tattoos are allergic reactions. The diagnostic work-up should include the tattoo ink used and, particularly in cases of scattered eczema, other products applied. Pigments penetrate very poorly into the epidermis and are not available as commercial test preparations. Consequently, patch tests very often show (false) negative results in affected individuals. Allergological individual diagnosis and assessment of clinical relevance are rarely possible as the chemical composition of the culprit tattoo ink is usually unknown.
Discussion
Diagnosis of tattoo allergy is challenging. The IVDK Tattoo Study 2.0 enables the identification of metals and pigments in skin samples, the preparation of individual patch test preparations with pigments, and the investigation of specific T lymphocytes in blood samples. In addition, assessment of the clinical relevance can be improved by exposure data and results of laboratory diagnostics.
期刊介绍：
Allergo Journal International is the official Journal of the German Society for Applied Allergology (AeDA) and the Austrian Society for Allergology and Immunology (ÖGAI). The journal is a forum for the communication and exchange of ideas concerning the various aspects of allergy (including related fields such as clinical immunology and environmental medicine) and promotes German allergy research in an international context. The aim of Allergo Journal International is to provide state of the art information for all medical and scientific disciplines that deal with allergic, immunological and environmental diseases. Allergo Journal International publishes original articles, reviews, short communications, case reports, and letters to the editor. The articles cover topics such as allergic, immunological and environmental diseases, the latest developments in diagnosis and therapy as well as current research work concerning antigens and allergens and aspects related to occupational and environmental medicine. In addition, it publishes clinical guidelines and position papers approved by expert panels of the German, Austrian and Swiss Allergy Societies.
All submissions are reviewed in single-blind fashion by at least two reviewers.
Originally, the journal started as a German journal called Allergo Journal back in 1992. Throughout the years, English articles amounted to a considerable portion in Allergo Journal. This was one of the reasons to extract the scientific content and publish it in a separate journal. Hence, Allergo Journal International was born and now is the international continuation of the original German journal. Nowadays, all original content is published in Allergo Journal International first. Later, selected manuscripts will be translated and published in German and included in Allergo Journal.
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