温迪亚地区异常子宫出血妇女的子宫内膜组织病理学研究

Medha Singh Tiwari, Priyanka Agrawal, S.K Sutrakar, Santosh Singh, Neha Khatik
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摘要

:任何月经频率、经量持续时间/失血量的改变都被称为异常子宫出血/AUB。在妇科门诊就诊的所有患者中,近 30% 都是因为 AUB 而就诊。本研究在温迪亚地区进行,目的是研究主诉异常出血模式的妇女的子宫内膜组织病理学:这项回顾性研究的对象是 2020 年 1 月至 2021 年 6 月期间在妇产科接受子宫内膜活检或子宫切除术并被送往雷瓦(MP)SSMC 病理科组织病理学部门的 200 名 AUB 妇女。收到福尔马林固定标本后先进行大体检查,然后进行处理,再用 H&E 染色法染色,最后进行显微镜检查。数据和病史由患者本人和护理人员提供:所有年龄组均可观察到 AUB。月经过多(105 名患者,52.5%)是 AUB 病例中最常见的出血模式,其次是月经过多(54 名患者,27%)。在我们的研究中,增生性子宫内膜(71 名患者,占 35.5%)是最常见的组织病理学诊断,其次是非非典型子宫内膜增生(45 名患者,占 22.5%)、分泌期(20 名患者,占 10%)、DPE(20 名患者,占 10%)、萎缩性子宫内膜(12 名患者,占 6%)、外源性激素(药片子宫内膜 10 名患者,占 5%)、良性腺瘤性息肉(9 名患者,占 4.AUB患者的子宫内膜活检和刮宫术中发现了不同的组织病理学结果。这项研究强调了子宫内膜活检及其组织病理学诊断对于正确治疗患者的重要性。
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Histopathology of endometrium in women presenting with abnormal uterine bleeding in Vindhya region
: Any alteration in frequency, flow duration/blood loss amount of menstruation is known as Abnormal uterine bleeding/AUB. Almost 30% of all patient attending gynaecology OPD are for AUB. This study was conducted in Vindhya region to study endometrial histopathology amongst women complaining of abnormal bleeding pattern: This retrospective study was conducted on 200 women presenting with AUB who undergone endometrial biopsy or hysterectomy in the Obstetrics and Gynaecology Department and sent to Histopathology section of Pathology department, SSMC, Rewa (MP) from Jan 2020 to June 2021. The formalin fixed specimens were received grossing done, followed by processing and then staining with H& E stain, followed by microscopy. Data & history was taken from the patient herself and attenders.: AUB was observed in all age groups. Menorrhagia (105 patients, 52.5%) was commonest bleeding pattern observed in cases of AUB, followed by Metrorrhagia (54 patients, 27%). In our study Proliferative endometrium (71 patients,35.5%) was most common histopathological diagnosis found, followed by Non-Atypical endometrial Hyperplasia (45 patients, 22.5%), Secretory phase (20 patients,10%), DPE (20 patients,10%), Atrophic endometrium (12 patients,6%), Exogenous hormone (pill endometrium 10 patients, 5%), Benign Adenomatous polyp (9 patients, 4.5%), Atypical endometrial Hyperplasia (5 patients, 2.5%), chronic endometritis (5 patients, 2.5%), Endometrial carcinoma (3 patients, 1.5%).Variable Histopathological findings are found in endometrial biopsy and curettage done in AUB patient. This study emphasizes the significance of endometrial biopsy and its histopathological diagnosis for proper patient management.
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