中国壮族 2 型糖尿病患者的代谢顺应性和心血管疾病风险现状

IF 2.3 4区 医学 Q3 ENDOCRINOLOGY & METABOLISM International Journal of Endocrinology Pub Date : 2023-12-22 DOI:10.1155/2023/1057121
Danqing Xu, Xia Dai, Qiong Yang, Xueying Li, Ying Xiao, Qiuhong Huang, undefined Qingqing Lou
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引用次数: 0

摘要

简介本研究旨在调查壮族 T2DM 患者的血糖、血压和血脂状况,并分析代谢监测依从性与心血管危险因素之间的相关性。研究方法2022 年 1 月至 8 月期间,广西壮族自治区三个地级市的四家三级甲等医院共对 1975 名壮族 T2DM 患者进行了评估。收集了实验室指标、生活方式和人口统计学特征。结果显示血糖、血压和血脂的达标率分别为 26.08%、45.77% 和 30.58%,三项指标均达标的患者仅占 5.06%。心血管疾病组的血糖、血压和血脂达标率分别为 32.92%、21.74% 和 9.94%。在心血管疾病组中,降糖药、降压药和降脂药的使用率分别为 77.54%、3.17% 和 4.11%。二元逻辑回归分析显示,年龄较大(OR = 1.033,95% CI [1.016,1.050])、女性(OR = 0.402,95% CI [0.260,0.621])、吸烟(OR = 1.994,95% CI [1.361,2.922])、血压不达标+使用降压药(OR = 0.348,95% CI [0.230,0.527])和血脂不达标+使用降脂药(OR = 0.244,95% CI [0.142,0.417])是心血管疾病的危险因素,而中等强度运动(OR = 0.439,95% CI [0.300,0.640])对心血管疾病有保护作用。结论高龄、女性、吸烟、血脂水平和血压不达标是心血管疾病的危险因素,而中等强度的运动对心血管疾病有保护作用。
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Current Status of Metabolic Compliance and Risk of Cardiovascular Disease in Patients with Type 2 Diabetes in the Zhuang Population in China
Introduction. This study aimed to investigate the blood glucose, blood pressure, and blood lipid status in Zhuang patients with T2DM and to analyze the correlation between compliance with metabolic monitoring and cardiovascular risk factors. Methods. A total of 1975 Zhuang patients with T2DM were evaluated in four Class III Grade A hospitals in three prefecture-level cities in the Guangxi Zhuang Autonomous Region between January and August 2022. Laboratory indicators, lifestyle, and demographic characteristics were collected. Results. The compliance rates for blood glucose, blood pressure, and blood lipids were 26.08%, 45.77%, and 30.58%, respectively, and only 5.06% of the patients reached the standard in all three indices. The compliance rates for blood glucose, blood pressure, and blood lipids in the CVD group were 32.92%, 21.74%, and 9.94%, respectively. In the CVD group, the usage rates of hypoglycemic, antihypertensive, and lipid-lowering drugs were 77.54%, 3.17%, and 4.11%, respectively. Binary logistic regression analysis showed that older age (OR = 1.033, 95% CI [1.016, 1.050]), female (OR = 0.402, 95% CI [0.260, 0.621]), smoke (OR = 1.994, 95% CI [1.361, 2.922]), blood pressure noncompliance + use of antihypertensive drugs (OR = 0.348, 95% CI [0.230, 0.527]), and blood lipid noncompliance + use of lipid-lowering drugs (OR = 0.244, 95% CI [0.142, 0.417]) were risk factors for CVDs, and moderate-intensity exercise (OR = 0.439, 95% CI [0.300,0.640]) was protective against CVD. Conclusions. Older age, female, smoke, blood lipid levels, and blood pressure noncompliance were risk factors for CVD while moderate-intensity exercise was observed to be protective.
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来源期刊
International Journal of Endocrinology
International Journal of Endocrinology ENDOCRINOLOGY & METABOLISM-
CiteScore
5.20
自引率
0.00%
发文量
147
审稿时长
1 months
期刊介绍: International Journal of Endocrinology is a peer-reviewed, Open Access journal that provides a forum for scientists and clinicians working in basic and translational research. The journal publishes original research articles, review articles, and clinical studies that provide insights into the endocrine system and its associated diseases at a genomic, molecular, biochemical and cellular level.
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