乳腺癌术后乳房和胸壁无症状神经病变的超声显示和靶向治疗。

Petra Steyerova, Martina Zimovjanova, Lukas Lambert, Andrea Burgetova
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摘要

目的:评估超声波(US)在乳腺癌术后神经病理性疼痛患者中识别神经病变的可行性,并评估 US 引导的针对性治疗的效果:乳腺癌术后神经痛患者接受超声检查。在 US 引导下使用局麻药和皮质类固醇的混合物治疗 US 发现的神经损伤。患者以 100 分制报告疼痛缓解情况(0% = 无效果,100% = 完全缓解)及其在未来 18 个月内的持续时间:我们对 11 名妇女进行了 17 次干预。结果:我们对 11 名女性进行了 17 次干预,发现 2 名患者出现神经瘤,5 名患者出现神经水肿,4 名患者出现神经瘢痕。受影响的神经包括肋间神经(5 例)、胸长神经(4 例)、胸神经皮支(1 例)以及肋间神经和胸长神经(1 例)。经过 15 次(88%)干预后,患者的症状得到缓解(55±32%),中位持续时间为 3 个月(0.5-18 个月):结论:在乳腺癌手术后的患者中,超声波能可靠地识别小的疼痛神经病变,并能通过超声波引导干预进行有效治疗。
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Ultrasound appearance and targeted therapy of symptomatic neural lesions in the breast and chest wall after breast cancer surgery.

Aim: To evaluate the feasibility of ultrasound (US) in identification of nerve lesions after breast cancer surgery in patients with neuropathic pain and assess the effect of a targeted US-guided therapy.

Material and methods: Patients with neuropathic pain after breast cancer surgery underwent US examination. Nerve lesions identified by US were treated by a US-guided application of a mixture of local anesthetics and corticoids. The patients reported pain relief on a 100-point scale (0% = no effect, 100% = complete relief) and its duration in the next 18 months.

Results: We performed 17 interventions in 11 women. A neuroma was observed in 2 patients, edema of the nerve in 5 patients, and scarring across the nerve in 4 patients. The affected nerves were the intercostobrachial nerve (5 patients), the long thoracic nerve (4), cutaneous branch of the pectoral nerve (1), and both the intercostobrachial and the long thoracic nerve (1). After 15 (88%) interventions, the patients reported relief (55±32%) with a median duration of 3 months (0.5-18 months).

Conclusion: In patients after breast cancer surgery, ultrasound can reliably identify small painful neural lesions which can be efficiently treated by ultrasound-guided intervention.

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