斯坦福 B 型主动脉壁内血肿保守治疗和血管内治疗后的效果--一项单中心回顾性研究。

Vascular and endovascular surgery Pub Date : 2024-07-01 Epub Date: 2023-12-29 DOI:10.1177/15385744231225888
Heiner Nebelung, Ralf-Thorsten Hoffmann, Verena Plodeck, Marvin Kapalla, Bianca Bohmann, Albert Busch, Norbert Weiss, Christian Reeps, Steffen Wolk
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引用次数: 0

摘要

目的:主动脉壁内血肿(IMH)是一种罕见疾病。迄今为止,只有有限的数据可供参考,而且保守治疗和血管内治疗的适应症尚未明确。本研究旨在调查 B 型主动脉膜内血肿患者的临床表现、病程、CT 影像特征和预后:我们在这项回顾性单中心研究中纳入了 2012 年至 2021 年间所有 B 型 IMHs 患者。对治疗前后的临床数据、定位、IMHs厚度和溃疡样突起(ULPs)的存在情况进行了评估:共发现 35 名患者(20 名女性;70.3 岁 ± 11 岁)。几乎所有的 IMH(34 例)都是自发性的,并伴有背痛症状(34 例)。在确诊时,9 名患者被认为需要进行 TEVAR,26 名患者主要接受保守治疗。在随访期间,又有 16 名患者被认为需要进行 TEVAR。接受血管内治疗和保守治疗的患者在治疗后厚度都有所下降。没有 ULP 的患者比有 ULP 的患者更常表现出 IMH 完全消退(血管内治疗 90.9% (10/11) vs 71.4% (5/7);保守治疗 71.4% (10/14) vs 33.3% (1/3);P = .207)。32%的患者在TEVAR术后出现并发症,而以保守治疗为主的患者并发症发生率更高(37.5% vs 22.2%)。随访期间未发现院内死亡率:无论是手术治疗还是保守治疗,IMH的预后似乎都很好。结论:无论是手术治疗还是保守治疗,IMH患者的预后似乎都很好。然而,有必要识别保守治疗下并发症的高风险患者,因此这些患者应接受TEVAR治疗。在我们的研究中,ULPs 似乎是重塑的不利因素。
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Outcome After Conservative and Endovascular Treatment of Stanford Type B Aortic Intramural Hematomas - A Single-Center Retrospective Study.

Objectives: Aortic intramural hematoma (IMH) is a rare disease. Thus far, only limited data is available and the indications for conservative and endovascular treatment are not well defined. The aim of this study was to investigate clinical presentation, course, CT imaging features and outcome of patients with type B aortic IMHs.

Methods: We included all patients with type B IMHs between 2012 and 2021 in this retrospective monocentric study. Clinical data, localization, thickness of IMHs and the presence of ulcer-like projections (ULPs) was evaluated before and after treatment.

Results: Thirty five patients (20 females; 70.3 y ± 11 y) were identified. Almost all IMHs (n = 34) were spontaneous and symptomatic with back pain (n = 34). At the time of diagnosis, TEVAR was deemed indicated in 9 patients, 26 patients were treated primarily conservatively. During the follow-up, in another 16 patients TEVAR was deemed indicated. Endovascularly and conservatively treated patients both showed decrease in thickness after treatment. Patients without ULPs showed more often complete resolution of the IMH than patients with ULPs (endovascularly treated 90.9% (10/11) vs 71.4% (5/7); conservatively treated 71.4% (10/14) vs 33.3% (1/3); P = .207). Complications after TEVAR occurred in 32% and more frequently in patients treated primarily conservatively (37.5% vs 22.2%). No in-hospital mortality was observed during follow-up.

Conclusions: Prognosis of IMH seems favourable in both surgically as well as conservatively treated patients. However, it is essential to identify patients at high risk for complications under conservative treatment, who therefore should be treated by TEVAR. In our study, ULPs seem to be an adverse factor for remodeling.

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