最新发展与未来展望:癌症治疗中的纳米给药系统

IF 2.8 3区 化学 Q2 CHEMISTRY, APPLIED Topics in Catalysis Pub Date : 2024-01-02 DOI:10.1007/s11244-023-01893-6
Sasireka Rajendran, Sai Nandhini Ravi, Vaishnavi M. Nair, R. Pooja Sree, Azhagu Saravana Babu Packirisamy, Jeyanthi Palanivelu
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引用次数: 0

摘要

纳米技术在纳米药物制剂生产方面的快速发展为改进癌症治疗技术带来了巨大希望。纳米医药产品为开发复杂的靶向方法和多功能性提供了可能。纳米技术已被用于细胞外癌症生物标志物和癌细胞的检测,以及体内成像、灵敏度和选择性、准确性和多重检测能力。事实上,纳米粒子不仅有可能解决传统癌症诊断和治疗的局限性,而且有可能为肿瘤检测和治疗开辟全新的可能性和发展尖端技术。纳米载体用于提高靶肿瘤细胞的特异性和向肿瘤部位递送药物的能力,在提高疗效的同时减少不必要的副作用。对外源性或内源性刺激做出反应的纳米载体已成为靶向给药的一种有前途的替代方法。本综述讨论了纳米粒子系统对肺癌、乳腺癌、黑色素瘤、结直肠癌、膀胱癌等癌症类型的干预。此外,还重点介绍了纳米载体在癌症诊断和治疗中的应用。这篇重要综述深入探讨了基于纳米载体的癌症疗法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recent Development and Future Aspects: Nano-Based Drug Delivery System in Cancer Therapy

The rapid advancement of nanotechnology in the production of nanomedicine agents holds enormous promise for improving cancer therapy techniques. Nanomedicine products offer the possibility of developing complex targeting approaches as well as multifunctionality. Nanotechnology has been examined for the detection of extracellular cancer biomarkers and cancer cells, as well as in vivo imaging, sensitive and selective, accuracy, and multiplexed detection capacity. In fact, nanoparticles have the potential to not only address the limitations of traditional cancer diagnosis and treatment, but also to open up entirely new possibilities and develop cutting-edge technology for tumour detection and treatment. Nano carriers are used to increase target tumour cell specificity and delivery capability to the tumour site, enhancing therapy efficacy while reducing unwanted side effects. Nanocarriers that respond to exogenous or endogenous stimuli have emerged as a promising alternative to target drug delivery. In this review intervention of nanoparticle system for cancer types like Lung cancer, Breast cancer, Melanoma, Colorectal cancer, Bladder cancer are discussed. Further focused on the advancement of nanocarriers for cancer diagnosis and treatment. The critical review takes deeper insight on nanocarrier-based cancer therapy.

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来源期刊
Topics in Catalysis
Topics in Catalysis 化学-物理化学
CiteScore
5.70
自引率
5.60%
发文量
197
审稿时长
2 months
期刊介绍: Topics in Catalysis publishes topical collections in all fields of catalysis which are composed only of invited articles from leading authors. The journal documents today’s emerging and critical trends in all branches of catalysis. Each themed issue is organized by renowned Guest Editors in collaboration with the Editors-in-Chief. Proposals for new topics are welcome and should be submitted directly to the Editors-in-Chief. The publication of individual uninvited original research articles can be sent to our sister journal Catalysis Letters. This journal aims for rapid publication of high-impact original research articles in all fields of both applied and theoretical catalysis, including heterogeneous, homogeneous and biocatalysis.
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