具有免疫反应和 Ornstein-Uhlenbeck 过程的登革热感染随机宿主内模型分析

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-01-02 DOI:10.1007/s00332-023-10004-4
Qun Liu, Daqing Jiang
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引用次数: 0

摘要

本文假设特定变量满足奥恩斯坦-乌伦贝克过程,建立了一个具有免疫反应的宿主内登革热随机模型,以进一步了解登革热的传播动力学。然后,我们详细分析了该随机系统的动力学特性,包括全局解的存在性和唯一性、静态分布的存在性以及受感染单核细胞和游离病毒的消亡。特别值得揭示的是,我们得到了随机系统准流行平衡周围概率密度中协方差矩阵的特定形式。最后,我们通过数值示例来证实我们的理论发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Analysis of a Stochastic Within-Host Model of Dengue Infection with Immune Response and Ornstein–Uhlenbeck Process

In this paper, assuming the certain variable satisfies the Ornstein–Uhlenbeck process, we formulate a stochastic within-host dengue model with immune response to obtain further understanding of the transmission dynamics of dengue fever. Then we analyze the dynamical properties of the stochastic system in detail, including the existence and uniqueness of the global solution, the existence of a stationary distribution, and the extinction of infected monocytes and free viruses. In particular, it is worth revealing that we get the specific form of covariance matrix in its probability density around the quasi-endemic equilibrium of the stochastic system. Finally, numerical illustrative examples are depicted to confirm our theoretical findings.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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