根据便秘患者的表型,进食后结肠转运反应与自我报告的便秘严重程度之间的关系。

IF 3.3 3区 医学 Q2 CLINICAL NEUROLOGY Journal of Neurogastroenterology and Motility Pub Date : 2024-01-30 DOI:10.5056/jnm21091
David Deutsch, Michel Bouchoucha, Julien Uzan, Gheorghe Airinei, Jean-Marc Sabate, Robert Benamouzig
{"title":"根据便秘患者的表型,进食后结肠转运反应与自我报告的便秘严重程度之间的关系。","authors":"David Deutsch, Michel Bouchoucha, Julien Uzan, Gheorghe Airinei, Jean-Marc Sabate, Robert Benamouzig","doi":"10.5056/jnm21091","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/aims: </strong>Eating is the major synchronizer of gastrointestinal motility and secretions. The present study aims to evaluate the interplay between self-perceived constipation severity (CS) and colonic response to eating in constipated patients according to the phenotype.</p><p><strong>Methods: </strong>We included 387 consecutive outpatients complaining of Rome IV chronic idiopathic constipation. Likert scales for CS, abdominal pain severity, bloating severity, depression and anxiety assessment, total and segmental colonic transit time (CTT), and colonic transit response to eating (CTRE) were performed in all patients.</p><p><strong>Results: </strong>Of the 387 patients included (49.7 ± 16.4 years), 320 (83%) were female, 203 had irritable bowel syndrome with constipation (IBS-C), 184 as functional constipation (FC), and 283 had defecation disorders (DD). The female gender was characterized by increased bloating severity (<i>P</i> = 0.011) and decreased Bristol stool form (<i>P</i> = 0.002). In IBS-C and FC patients, CS was related with bloating severity (<i>P</i> < 0.001 in both groups) and total CTT (<i>P</i> = 0.007 in IBS-constipation, <i>P</i> = 0.040 in FC). In IBS-C patients, CS was also associated with abdominal pain severity (<i>P</i> = 0.003) and Bristol stool form (<i>P</i> = 0.004). In contrast, in FC, CS was only related to left CTRE (<i>P</i> = 0.006), and in patients with DD, CS was associated with total CTT (<i>P</i> < 0.001) and left CTRE (<i>P</i> = 0.002).</p><p><strong>Conclusion: </strong>Colonic transit response to eating was not associated to CS in IBS-C patients, but left CTRE was associated with constipation severity in FC and DD patients.</p>","PeriodicalId":16543,"journal":{"name":"Journal of Neurogastroenterology and Motility","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774807/pdf/","citationCount":"0","resultStr":"{\"title\":\"Relationship Between Colonic Transit Response to Eating With Self-reported Constipation Severity in Constipated Patients According to the Phenotype.\",\"authors\":\"David Deutsch, Michel Bouchoucha, Julien Uzan, Gheorghe Airinei, Jean-Marc Sabate, Robert Benamouzig\",\"doi\":\"10.5056/jnm21091\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background/aims: </strong>Eating is the major synchronizer of gastrointestinal motility and secretions. The present study aims to evaluate the interplay between self-perceived constipation severity (CS) and colonic response to eating in constipated patients according to the phenotype.</p><p><strong>Methods: </strong>We included 387 consecutive outpatients complaining of Rome IV chronic idiopathic constipation. Likert scales for CS, abdominal pain severity, bloating severity, depression and anxiety assessment, total and segmental colonic transit time (CTT), and colonic transit response to eating (CTRE) were performed in all patients.</p><p><strong>Results: </strong>Of the 387 patients included (49.7 ± 16.4 years), 320 (83%) were female, 203 had irritable bowel syndrome with constipation (IBS-C), 184 as functional constipation (FC), and 283 had defecation disorders (DD). The female gender was characterized by increased bloating severity (<i>P</i> = 0.011) and decreased Bristol stool form (<i>P</i> = 0.002). In IBS-C and FC patients, CS was related with bloating severity (<i>P</i> < 0.001 in both groups) and total CTT (<i>P</i> = 0.007 in IBS-constipation, <i>P</i> = 0.040 in FC). In IBS-C patients, CS was also associated with abdominal pain severity (<i>P</i> = 0.003) and Bristol stool form (<i>P</i> = 0.004). In contrast, in FC, CS was only related to left CTRE (<i>P</i> = 0.006), and in patients with DD, CS was associated with total CTT (<i>P</i> < 0.001) and left CTRE (<i>P</i> = 0.002).</p><p><strong>Conclusion: </strong>Colonic transit response to eating was not associated to CS in IBS-C patients, but left CTRE was associated with constipation severity in FC and DD patients.</p>\",\"PeriodicalId\":16543,\"journal\":{\"name\":\"Journal of Neurogastroenterology and Motility\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-01-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10774807/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Neurogastroenterology and Motility\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5056/jnm21091\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Neurogastroenterology and Motility","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5056/jnm21091","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

摘要

背景/目的:进食是胃肠道蠕动和分泌的主要同步器。本研究旨在根据表型评估便秘患者自我感觉的便秘严重程度(CS)与结肠对进食的反应之间的相互作用:我们纳入了 387 名主诉患有罗马 IV 型慢性特发性便秘的连续门诊患者。对所有患者进行了CS、腹痛严重程度、腹胀严重程度、抑郁和焦虑评估、结肠总通过时间(CTT)和节段性结肠通过时间(CTT)以及进食后结肠通过反应(CTRE)的李克特量表测量:在纳入的 387 名患者(49.7 ± 16.4 岁)中,320 人(83%)为女性,203 人患有肠易激综合征伴便秘(IBS-C),184 人患有功能性便秘(FC),283 人患有排便障碍(DD)。女性的特点是腹胀严重程度增加(P = 0.011)和布里斯托粪便形态减少(P = 0.002)。在 IBS-C 和 FC 患者中,CS 与腹胀严重程度(两组中的 P 均小于 0.001)和 CTT 总量(IBS-便秘患者中的 P = 0.007,FC 患者中的 P = 0.040)有关。在 IBS-C 患者中,CS 还与腹痛严重程度(P = 0.003)和布里斯托粪便形态(P = 0.004)相关。相反,在 FC 患者中,CS 仅与左侧 CTRE 相关(P = 0.006),而在 DD 患者中,CS 与总 CTT(P < 0.001)和左侧 CTRE(P = 0.002)相关:结论:IBS-C 患者进食后的结肠转运反应与 CS 无关,但左侧 CTRE 与 FC 和 DD 患者的便秘严重程度有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Relationship Between Colonic Transit Response to Eating With Self-reported Constipation Severity in Constipated Patients According to the Phenotype.

Background/aims: Eating is the major synchronizer of gastrointestinal motility and secretions. The present study aims to evaluate the interplay between self-perceived constipation severity (CS) and colonic response to eating in constipated patients according to the phenotype.

Methods: We included 387 consecutive outpatients complaining of Rome IV chronic idiopathic constipation. Likert scales for CS, abdominal pain severity, bloating severity, depression and anxiety assessment, total and segmental colonic transit time (CTT), and colonic transit response to eating (CTRE) were performed in all patients.

Results: Of the 387 patients included (49.7 ± 16.4 years), 320 (83%) were female, 203 had irritable bowel syndrome with constipation (IBS-C), 184 as functional constipation (FC), and 283 had defecation disorders (DD). The female gender was characterized by increased bloating severity (P = 0.011) and decreased Bristol stool form (P = 0.002). In IBS-C and FC patients, CS was related with bloating severity (P < 0.001 in both groups) and total CTT (P = 0.007 in IBS-constipation, P = 0.040 in FC). In IBS-C patients, CS was also associated with abdominal pain severity (P = 0.003) and Bristol stool form (P = 0.004). In contrast, in FC, CS was only related to left CTRE (P = 0.006), and in patients with DD, CS was associated with total CTT (P < 0.001) and left CTRE (P = 0.002).

Conclusion: Colonic transit response to eating was not associated to CS in IBS-C patients, but left CTRE was associated with constipation severity in FC and DD patients.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Neurogastroenterology and Motility
Journal of Neurogastroenterology and Motility GASTROENTEROLOGY & HEPATOLOGY-CLINICAL NEUROLOGY
CiteScore
6.30
自引率
8.80%
发文量
96
期刊介绍: Journal of Neurogastroenterology and Motility (J Neurogastroenterol Motil) is a joint official journal of the Korean Society of Neurogastroenterology and Motility, the Thai Neurogastroenterology and Motility Society, the Japanese Society of Neurogastroenterology and Motility, the Indian Motility and Functional Disease Association, the Chinese Society of Gastrointestinal Motility, the South East Asia Gastro-Neuro Motility Association, the Taiwan Neurogastroenterology and Motility Society and the Asian Neurogastroenterology and Motility Association, launched in January 2010 after the title change from the Korean Journal of Neurogastroenterology and Motility, published from 1994 to 2009.
期刊最新文献
Effectiveness of Abdominal Massage Versus Kinesio Taping in Women With Chronic Constipation: A Randomized Controlled Trial. Phrenic Ampulla Emptying Dysfunction in Patients with Esophageal Symptoms. The Impact of a Twice-daily Versus Once-daily Proton Pump Inhibitor Dosing Regimen on Laryngopharyngeal Reflux Symptoms: A Prospective Randomized Controlled Trial. Additional Diagnostic Yield of the Rapid Drink Challenge in Chicago Classification Version 4.0 Compared With Version 3.0. Clinicians' Knowledge, Attitudes, and Practices Regarding the Management of Functional Gastrointestinal Disorders With Neuromodulators and Psychological Treatment.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1