{"title":"克隆博美犬的 X 型脱发症。","authors":"Sébastien Deleporte, Pascal Prelaud, Catherine Laffort","doi":"10.1111/vde.13234","DOIUrl":null,"url":null,"abstract":"<p><p>A two-year-old Pomeranian dog with Alopecia X was cloned after accidental death. Despite earlier castration, the cloned animal developed the same lesions of Alopecia X at the same age. This observation suggests that the disease is due to genetically programmed hair cycle arrest without strong environmental influences.</p>","PeriodicalId":23599,"journal":{"name":"Veterinary dermatology","volume":" ","pages":"194-196"},"PeriodicalIF":1.9000,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Alopecia X in a cloned Pomeranian dog.\",\"authors\":\"Sébastien Deleporte, Pascal Prelaud, Catherine Laffort\",\"doi\":\"10.1111/vde.13234\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A two-year-old Pomeranian dog with Alopecia X was cloned after accidental death. Despite earlier castration, the cloned animal developed the same lesions of Alopecia X at the same age. This observation suggests that the disease is due to genetically programmed hair cycle arrest without strong environmental influences.</p>\",\"PeriodicalId\":23599,\"journal\":{\"name\":\"Veterinary dermatology\",\"volume\":\" \",\"pages\":\"194-196\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Veterinary dermatology\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1111/vde.13234\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/2 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Veterinary dermatology","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1111/vde.13234","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/2 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
摘要
一只患有 X 型脱发症的两岁博美犬在意外死亡后被克隆。尽管克隆动物较早地进行了阉割，但在相同的年龄却出现了相同的 X 型脱发病变。这一观察结果表明，这种疾病是由于基因程序导致的毛发周期停滞而引起的，并没有受到强烈的环境影响。
A two-year-old Pomeranian dog with Alopecia X was cloned after accidental death. Despite earlier castration, the cloned animal developed the same lesions of Alopecia X at the same age. This observation suggests that the disease is due to genetically programmed hair cycle arrest without strong environmental influences.
期刊介绍：
Veterinary Dermatology is a bi-monthly, peer-reviewed, international journal which publishes papers on all aspects of the skin of mammals, birds, reptiles, amphibians and fish. Scientific research papers, clinical case reports and reviews covering the following aspects of dermatology will be considered for publication:
-Skin structure (anatomy, histology, ultrastructure)
-Skin function (physiology, biochemistry, pharmacology, immunology, genetics)
-Skin microbiology and parasitology
-Dermatopathology
-Pathogenesis, diagnosis and treatment of skin diseases
-New disease entities
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