中度急性营养不良儿童即食补充食品有效性的现有证据:系统回顾和荟萃分析。

IF 2.4 Q3 NUTRITION & DIETETICS Journal of Nutritional Science Pub Date : 2024-01-03 eCollection Date: 2023-01-01 DOI:10.1017/jns.2023.114
Melese Sinaga Teshome, Tefera Belachew Lema, Teklu Gemechu Abessa, Sarah Mingels, Marita Granitzer, Eugene Rameckers, Evi Verbecque
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引用次数: 0

摘要

中度急性营养不良(MAM)的定义是体重身高 Z 值(WHZ)介于世界卫生组织参考值的-3 和-2 之间,或中上臂周长(MUAC)≥11⋅5,P = 0⋅01, I² = 97 %)与其他膳食干预措施相比,对中度急性营养不良儿童(n 6476)不同人体测量指标的影响。将 RUSF 与玉米-大豆混合加加(CSB++)进行比较后发现,与接受 CSB++ 的儿童相比,RUSF 对儿童人体测量的影响较小,但效果显著(汇总平均值:0⋅16;95 % CI = [0⋅05, 0⋅27], P = 0⋅01; I2 = 35 %)。与接受 CSB++ 治疗的 MAM 儿童相比,接受 RUSF 治疗的 MAM 儿童的康复率更高(汇总风险差异:0⋅11;95 % CI = [0⋅06, 0⋅11], P < 0⋅001; I2 = 0 %)。与其他膳食干预措施相比,RUSF 干预措施似乎有望改善地中海贫血症儿童的营养状况和康复率。
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Current evidence on the effectiveness of Ready-to-Use Supplementary Foods in children with moderate acute malnutrition: a systematic review and meta-analysis.

Moderate acute malnutrition (MAM) is defined by a weight-for-height Z-score (WHZ) between -3 and -2 of the WHO reference or by a mid-upper arm circumference (MUAC) of ≥11⋅5 and <12⋅5 cm. This study aimed to synthesise the evidence for the effectiveness of Ready-to-Use Supplementary Food (RUSF) compared to other dietary interventions or no intervention on functioning at different levels of the International Classification of Functioning, Disability, and Health (ICF) among children with MAM between 2 and12 years old. Three databases (PubMed, Scopus, and Web of Science) were systematically searched (last update: 20 November 2022). Pooled estimates of effect were calculated using random-effects meta-analyses. The level of evidence was estimated with the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method. Seven studies were included. RUSF had a significant small-sized better effect (pooled mean: 0⋅38; 95 % CI = [0⋅10, 0⋅67], P = 0⋅01, I² = 97 %) on different anthropometric measurements compared to other dietary interventions among MAM children (n 6476). Comparing RUSF with corn-soy blend Plus Plus (CSB++) showed that RUSF had a small-sized but significantly better effect on the children's anthropometric measures compared to children who received CSB++ (pooled mean: 0⋅16; 95 % CI = [0⋅05, 0⋅27], P = 0⋅01; I2 = 35 %). MAM children treated with RUSF had a better recovery rate compared to those treated with CSB++ (pooled risk difference: 0⋅11; 95 % CI = [0⋅06, 0⋅11], P < 0⋅001; I2 = 0 %). The RUSF intervention seems promising in improving MAM children's nutritional outcomes and recovery rate compared to other dietary interventions.

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来源期刊
Journal of Nutritional Science
Journal of Nutritional Science NUTRITION & DIETETICS-
CiteScore
3.00
自引率
0.00%
发文量
91
审稿时长
7 weeks
期刊介绍: Journal of Nutritional Science is an international, peer-reviewed, online only, open access journal that welcomes high-quality research articles in all aspects of nutrition. The underlying aim of all work should be, as far as possible, to develop nutritional concepts. JNS encompasses the full spectrum of nutritional science including public health nutrition, epidemiology, dietary surveys, nutritional requirements, metabolic studies, body composition, energetics, appetite, obesity, ageing, endocrinology, immunology, neuroscience, microbiology, genetics, molecular and cellular biology and nutrigenomics. JNS welcomes Primary Research Papers, Brief Reports, Review Articles, Systematic Reviews, Workshop Reports, Letters to the Editor and Obituaries.
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