中国推定眼结核的临床表现和长期随访

IF 1.9 Q3 INFECTIOUS DISEASES Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Pub Date : 2023-12-30 DOI:10.1016/j.jctube.2023.100413

Jing Xie , Ya Qu , Zhuyun Qian , Xiaohong Meng , Jun Lin , Yong Liu , Zhengqin Yin , Yong Tao , Shiying Li

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引用次数: 0

摘要

背景本研究旨在报告中国人群中推测的眼结核（OTB）的临床表现和抗结核治疗（ATT）后的治疗反应。方法回顾性分析中国两家眼科诊所2006年至2022年期间推测的OTB患者的临床数据，包括一般特征、眼部病变、基线视力和最终随访。观察到以下眼部表现：前葡萄膜炎（4.8%）、后葡萄膜炎（34.5%）、泛葡萄膜炎（11.9%）、视网膜血管炎（40.5%）和视神经病变（8.3%）。ATT后，视力有不同程度改善的有48眼（57.1%），保持稳定的有34眼（40.5%），视力下降的有2眼（2.4%）。临床特征必须与局部和一般实验室检查结果相结合，并与其他亚专科合作才能做出最终诊断。

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Clinical manifestation and long-term follow-up of presumed ocular tuberculosis in China

Background

This study aimed to report the clinical manifestations of presumed ocular tuberculosis (OTB) and the treatment response after anti-tuberculosis therapy (ATT) in a Chinese population.

Methods

Clinical data, including general characteristics, ocular lesions, visual acuity at baseline, and final follow-up of patients with presumed OTB from 2006 to 2022 in two eye clinics in China, were retrospectively analyzed.

Results

The study included 84 eyes of 52 patients. The following ocular manifestations were observed: anterior uveitis (4.8%), posterior uveitis (34.5%), panuveitis (11.9%), retinal vasculitis (40.5%) and optic neuropathy (8.3%). After ATT, the vision improved by varying degrees in 48 eyes (57.1%), remained stable in 34 eyes (40.5%) and decreased in 2 eyes (2.4%).

Conclusions

OTB is likely to be misdiagnosed as other infectious uveitis and optic neuropathy. Clinical features must be interpreted in conjunction with topical and general laboratory findings and in collaboration with other subspecialties to make a final diagnosis.

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来源期刊

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases Medicine-Pulmonary and Respiratory Medicine

CiteScore

4.00

自引率

5.00%

发文量

审稿时长

30 weeks

期刊介绍： Journal of Clinical Tuberculosis and Mycobacterial Diseases aims to provide a forum for clinically relevant articles on all aspects of tuberculosis and other mycobacterial infections, including (but not limited to) epidemiology, clinical investigation, transmission, diagnosis, treatment, drug-resistance and public policy, and encourages the submission of clinical studies, thematic reviews and case reports. Journal of Clinical Tuberculosis and Mycobacterial Diseases is an Open Access publication.