体外膜肺氧合与左心室减压疗法(ECPella)同时进行的新方法

Breah Paciotti MPH, PA-C , Pankaj Garg MBBS , James Postier , Amy Lykins APRN, DNP , Basar Sareyyupoglu MD
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引用次数: 0

摘要

经皮置入静脉-动脉体外膜肺氧合(VA-ECMO)常用于支持难治性心律失常或心跳骤停以及心源性休克恶化的患者。通过主动脉血液逆流进行外周体外膜肺氧合(VA-ECMO)会导致左心室(LV)后负荷显著增加。严重功能障碍的左心室可能无法克服这种后负荷来打开主动脉瓣并自行卸载。这可能导致左心室膨胀、左心室压力增加、冠状动脉血液循环不良、左心房压力增加、肺水肿和肺动脉高压。此外,这还会危及心室的恢复,尤其是在缺血导致心肌受损的情况下。此外,如果主动脉瓣在心动周期中一直处于关闭状态,左心室和主动脉根部的血液淤积可能会增加血栓形成的风险。这些并发症可能导致心脏功能无法恢复,患者也无法成为心脏移植的候选者。在心源性休克患者中,利用 Impella 与 VA-ECMO(通常称为 ECPella)可持续降低死亡率并改善预后。需要长期 ECPella 支持作为康复或移植桥梁的患者可能仍需卧床,因为使用 2 个机械循环支持装置的患者的行动具有挑战性。我们介绍了通过腋动脉 Y 型烟囱移植吻合术放置 ECPella 的技术,用于动脉插管和 Impella 插入,以及经皮插入右颈内静脉用于静脉插管。这种技术使 VA-ECMO 在局部麻醉的情况下就能方便地行走和拔管,而无需插管或前往手术室。
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A Novel Approach for Simultaneous Venoarterial Extracorporeal Membrane Oxygenation and Left Ventricular Decompression Therapy With Impella (ECPella)

Percutaneously placed veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is commonly used to support patients with refractory cardiac arrhythmias or arrest and worsening cardiogenic shock. Peripheral VA-ECMO by retrograde flow of blood in the aorta results in a significant increase in left ventricle (LV) afterload. A severely dysfunctional LV may be unable to overcome this afterload to open the aortic valve and unload itself. This may lead to LV distension, increased LV pressure, poor coronary blood circulation, increased left atrial pressures, pulmonary edema, and pulmonary hypertension. Moreover, it jeopardizes ventricular recovery, particularly in the presence of ischemia-induced myocardial impairment. Furthermore, if the aortic valve remains closed during the cardiac cycle, stasis of blood in the LV and aortic root may increase the risk of thrombus formation. These complications may preclude cardiac recovery and the patient from being a heart transplant candidate. In patients with cardiogenic shock, utilizing Impella with VA-ECMO, commonly referred to as ECPella, has consistently been shown to reduce mortality and improve outcomes. Patients who need prolonged ECPella support as a bridge to recovery or transplant may remain bed-bound since ambulation of patients with 2 mechanical circulatory support devices is challenging. We present the technique of ECPella placement through Y chimney graft anastomosis on the axillary artery for arterial cannula and Impella insertion and percutaneous cannulation of the right internal Jugular vein for venous cannula. This technique gives the ease of ambulation and decannulation of VA-ECMO under local anesthesia without requiring intubation or a trip to the operating room.

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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
59
期刊介绍: Operative Techniques in Thoracic and Cardiovascular Surgery provides richly illustrated articles on techniques in thoracic and cardiovascular surgery written by renowned surgeons. Each issue presents cardiothoracic topics in adult cardiac, congenital, and general thoracic surgery. Each specialty of interest to the thoracic and cardiovascular surgeon is explored through two different approaches to a specific surgical challenge. Each article is thoroughly illustrated with original line drawings, actual intraoperative photos, and supporting tables and graphs.
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