剖腹产双注射器脊髓麻醉技术的有效性研究

S. Acharya, Sabin Bhandari, Sushmita Bhandari
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引用次数: 0

摘要

使用高压布比卡因进行脊髓麻醉是剖腹产最常用的方法。芬太尼等辅助剂可增强感觉阻滞并提供稳定的血流动力学,通常与布比卡因预先混合在一个注射器中。芬太尼加入高压布比卡因后,会使溶液的密度降低到 0.0006,从而改变局部麻醉剂在 CSF 中的扩散。如果我们用不同的注射器分别注射这两种药物,可能会将两种药物的密度和 PH 值变化的影响降至最低,并在血流动力学改变最小的情况下产生最大效果。因此,本研究采用两种不同的注射器为剖腹产患者连续注射芬太尼和高压布比卡因,以观察感觉阻滞的质量和血流动力学反应。这项干预性研究对 79 名接受剖腹产手术的患者进行了脊髓麻醉,用两种不同的注射器依次注射 0.5%高压布比卡因 9 毫克(1.8 毫升)和芬太尼 20 微克。在 79 名产妇中,只有 22 人(27.85%)在剖腹产过程中出现低血压,需要使用血管舒张剂治疗,血管舒张剂的最大使用量为 15 毫克美芬丁胺。脊髓麻醉 20 分钟后最大感觉阻滞的平均水平为:20 名患者(25.32%)为 T2,19 名患者(24.05%)为 T3,32 名患者(40.51%)为 T4,1 名患者(1.27%)为 T5,7 名患者(8.86%)为 T6。患者对手术麻醉的术中质量非常满意。只有 6 名(7.59%)患者有轻微不适,无需任何药物治疗。这项研究的结果表明,单独鞘内注射芬太尼和高压布比卡因能更好地稳定血流动力学,提高手术麻醉的质量,使其能在脊髓更高的位置发挥作用,同时将剖腹产患者的其他副作用降到最低。
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Study of effectiveness of two syringe spinal anaesthesia technique for caesarean section
Spinal anaesthesia using hyperbaric bupivacaine is the most popular method for caesarean section. Adjuvents like fentanyl which enhances the sensory block and provide stable haemodynamics are usually premixed with bupivacaine in a single syringe. Fentanyl when added to hyperbaric bupivacaine, decreases the density of solution to extent of 0.0006 which alters the spread of local anesthetics in CSF. If we inject both the drugs separately in different syringe, it may minimize the effect of the changes in densities and PH of both the drugs and produce their maximum effect with minimal haemodynamic alteration. Therefore this study was conducted to see the quality of sensory block and haemodynamic response by sequential intrathecal administration of fentanyl and hyperbaric bupivacaine in two different syringe for patients undergoing caesarian section. This interventional study was carried out in Seventy nine Patients undergoing caesarean section under spinal anesthesia with 0.5% hyperbaric bupivacaine 9mg (1.8 ml) and fentanyl 20 mcg in two different syringe administered sequentially. Out of 79 parturients only 22 (27.85%) had hypotension requiring vasopressor treatment during caesarean section and maximum amount of vasopressor used was 15 mg of mephentermine. The mean level of maximum sensory block after 20 mins of spinal anaesthesia was T2 in 20 (25.32%) patients, T3 in 19 (24.05%) patients, T4 in 32 (40.51%) patients, T5 in 1 (1.27%) patient and T6 in 7 (8.86%) Patients. Intraoperative quality of surgical anaesthesia was very satisfactory to the patients. Only 6 (7.59%) patients had mild discomfort whithout requirement of any medical treatment. The result of this study concluded that separate intrathecal injection of fentanyl and hyperbaric bupivacaine provides better haemodynamic stability, improves quality of surgical anaethesia allowing it to work at higher levels in the spinal cord with minimal other side effects in patient undergoing caesarean section.
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