接受超声乳化手术患者的泪膜状态研究

Anjali Sharma, Hemlata Yadav, Poulomi Ghosh, Megha Gautam, Aditya Sharma
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摘要

本研究旨在研究接受乳化手术的患者术前和术后的泪膜状况。该研究是一项前瞻性研究,研究对象是 100 名接受乳化手术的患者,研究期限为 1 年。泪膜状态检查包括施尔默氏试验、用荧光素染料对角膜和结膜染色、泪膜破裂时间(TBUT),分别在超声乳化术前和术后进行。术前评估的平均施尔默值为 27.45±4.95,而术后第 7、15 和 30 天的施尔默值分别为 9.09±2.19、16.73±5.12 和 24.45±4.05。同样,术前的平均 TBUT 为 11.11±1.16,术后第 7 天降至 6.63±1.57,第 15 天降至 7.37±1.44,第 30 天降至 9.77±0.91。显著性检验(方差分析)显示,与基线值相比,术后各随访阶段的平均施尔默氏值和TBUT值均有显著统计学差异(P<0.01)。白内障手术可能会因切口本身以及术中显微镜光线照射而导致干眼症。因此,必须使用人工泪液来改善术后初期的生活质量。不过,泪膜状况会逐渐得到改善。我们只对患者进行了一个月的随访,建议进行长期随访,以评估泪膜恢复到术前状态所需的时间。
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Study of tear film status in patients undergoing phacoemulsification surgery
The present study was undertaken to study the tear film status preoperatively and post-operatively in patients undergoing phacoemulsification surgery. The study was conducted as prospective study on 100 patients undergoing phacoemulsification surgery during the study period of 1 year. Work up for tear film status including Schirmer’s test, staining of cornea and conjunctiva with fluorescein dye, TBUT (tear film break up time) was done preoperatively and postoperatively after phacoemulsification. Mean Schirmer’s value at preoperative assessment was 27.45±4.95 whereas that at post operative day 7, 15 and 30 was 9.09±2.19, 16.73±5.12 and 24.45±4.05 respectively. Similarly, mean TBUT at preoperative level was 11.11±1.16 which reduced to 6.63±1.57 at day 7, 7.37±1.44 at day 15 and 9.77±0.91 at day 30. Test of significance (ANOVA) showed statistically significant difference in mean Schirmer’s and TBUT values at various follow ups post-operatively as compared to baseline (p<0.01). Cataract surgery can lead to dry eye due to incision itself as well as due to intra-operative exposure to the microscope light. Thus, artificial tears must be prescribed to improve the quality of life during immediate post-operative period. However, gradually, tear film status improved. We only followed up patients till one month, a long term follow up is recommended to assess the time taken for the tear film to recover to its preoperative status.
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