治疗合并病变(静脉曲张和类风湿性关节炎)患者下肢营养性溃疡的经验

K. Gavrilov, V. А. Markina, K. S. Sevostyanova, A. I. Shevela
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引用次数: 0

摘要

下肢静脉曲张是地球上最常见的疾病之一,它与其他疾病的结合是不可避免的。疾病的合并会加重彼此的病情。类风湿性关节炎会加重静脉曲张的病程,并伴有营养障碍--这两种疾病都是独立存在的--促炎因子增加,微循环改变,肢体轴变形,肌肉骨骼功能受损,而类风湿性关节炎的治疗会降低机体的免疫反应,减少机体的修复能力。临床病例:患者患有长期类风湿性关节炎和静脉曲张。他曾长期使用细胞抑制药物,后来过渡到激素药物。约 5 年来,他发现双侧小腿出现溃疡,呈圆形,严重降低了生活质量,保守治疗无效。他多次接受住院治疗,静脉注射一般修复药物和血管药物。他还经常在居住地的综合诊所接受观察,对溃疡面进行局部治疗。患者先后接受了静脉内激光凝固皮下大静脉主干治疗静脉曲张。第二阶段是对伤口表面进行清创,并用游离穿孔皮瓣进行植皮。在两个阶段之间,根据临床建议进行药物治疗。类风湿性关节炎和静脉曲张会相互加重,尤其是营养性表现。对此类患者的治疗应由不同专业的专家团队共同完成。对这些患者进行循序渐进的治疗,并为每一位患者做好精心准备,可以取得良好的治疗效果。患者对治疗的承诺占有特殊地位。
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Experience in the lower extremities trophic ulcers treatment in patient with combined pathologies: varicose veins and rheumatoid arthritis
Varicose veins of the lower extremities is one of the most common diseases on Earth and its combination with other diseases is inevitable. The combination of diseases aggravates the course of each other. Rheumatoid arthritis worsens the course of varicose veins with trophic disorders – both independently – an increase in pro-inflammatory factors, a change in microcirculation, deformation of the limb axis with a violation of musculoskeletal function, and treatment of rheumatoid arthritis reduces the immune response of the body reducing the reparative capabilities of the body. Clinical case: a patient with a long course of rheumatoid arthritis and varicose veins. For a long time he used cytostatic drugs with a subsequent transition to hormonal drugs. For about 5 years, he noted the appearance of ulcers on both shins, which took a circular shape, which significantly reduced the quality of life and did not respond to conservative treatment. He repeatedly underwent inpatient treatment with intravenous administration of general restorative and vascular drugs. He was also constantly observed in the polyclinic at the place of residence with the implementation of local treatment of ulcerative surfaces. The patient was successively treated for varicose veins by endovenous laser coagulation of the trunks of large subcutaneous veins. The second stage was performed debridement of the wound surface and skin grafting with a free perforated flap. Between the stages, the appointment of drug therapy according to clinical recommendations. Rheumatoid arthritis and varicose veins aggravate each other, especially trophic manifestations. Treatment of such patients should be carried out by a team ofspecialists of various profiles together. Step-by-step treatment ofsuch patients with careful preparation for each of them shows excellent results. A special place is occupied by the patients’ commitment to treatment.
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