植物化学物质的双重作用:从植物的防御分子到人类的治疗药物

Niti Pathak, A. Tiku
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引用次数: 0

摘要

近年来,药用植物作为初级保健系统中的治疗成分受到了广泛关注。药用植物具有多种特性,因为它们含有生物活性化合物,包括生物碱、植物甾醇、黄酮类化合物、皂甙、萜类化合物、膳食纤维、肽等,这些化合物以不同的剂量存在于植物的不同部位。这些植物化学物质由植物自身产生,用于防御,但使用者提取这些物质是为了获得抗菌和治疗功效。有关利用植物部分治疗疾病和促进健康的知识在土著社区口口相传,历久弥新。然而,在自然界中,资源的过度开发已导致具有高治疗价值的药用植物枯竭。植物组织培养、新陈代谢工程和其他现代技术的引入,大规模生产了这些具有高浓度生物活性成分的植物。因此,将从当地社区收集到的信息与通过传统和现代技术大规模生产次生代谢物并将其用于疾病治疗相结合,是实现健康的基础。
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Phytochemicals in Bifunctional Roles: From Defense Molecules in Plants to Therapeutic Agents in Humans
Medicinal plants have gained a lot of interest in the recent past as healing components in the primary health care system. They possess a multitude property due to the presence of bioactive compounds which include alkaloids, phytosterols, flavonoids, saponins, terpenoids, dietary fibers, peptides, etc. in varied dosages and in different parts of the plant. These phytochemicals are produced by plants for their defense but are extracted by users for their antimicrobial and healing properties. Knowledge about the usage of plant parts in curing ailment and health promotion has been passed orally through indigenous communities for ages. However, in nature, overexploitation of resources has led to the depletion of medicinal plants of high therapeutic value. Introduction of plant tissue culture, metabolic engineering, and other modern techniques have shown mass-scale production of these plants with high concentrations of bioactive components. Thus, an amalgamation of information gathered from local communities along with large-scale production of secondary metabolites through traditional and modern techniques and their utilization in disease treatment is the basis for good health.
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