巨细胞病毒食管炎与免疫功能正常宿主的杓状囊肿有关

S. Anchan, Anjali Khialani, Athira Raj
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引用次数: 0

摘要

CMV食管炎通常发生在免疫力低下的人身上,而免疫力正常的人食管很少受到影响。据我所知,与杓状肌瘤囊肿相关的 CMV 食管炎在文献中尚未见报道,如果囊肿切除后复发,则可考虑该病。 本研究的目的是报告一名免疫功能正常患者的 CMV 独特表现。一位免疫功能正常的中年女士出现吞咽困难,被诊断为杓状囊肿。上食管活检发现巨细胞病毒包涵体,并进行了免疫学检测以确认病理。 囊肿切除术后复发。再次切除囊肿后,患者需要静脉注射更昔洛韦。目前,抗病毒药物在治疗免疫功能正常者的 CMV 食管炎中的作用尚未得到很好的确定。在切除囊肿后,我们对该患者进行了一个疗程的更昔洛韦治疗,取得了良好的效果。巨细胞病毒上食管受累的罕见性、与杓状囊肿的关联性以及抗病毒药物在免疫功能正常患者治疗中的实用性,使得本病例报告变得独特而有趣。
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Cytomegalovirus esophagitis associated with arytenoid cyst in an immunocompetent host
CMV esophagitis is usually encountered in immunocompromised individuals and esophagus is rarely affected in immunocompetent individuals. CMV esophagitis associated with arytenoid cyst has not yet been reported in literature to the best of my knowledge and can be considered in case of recurrence of cyst following excision.  The objective of this study is to report the unique presentation of CMV in an immunocompetent patient. A middle-aged immunocompetent lady presenting with dysphagia was diagnosed to have arytenoid cyst. Biopsy from upper esophagus revealed cytomegalovirus inclusion bodies and immunological test were performed to confirm the pathology.  The cyst excision lead to recurrence. It was excised again followed by a course of intravenous ganciclovir. Currently, the role of antiviral in treatment of CMV esophagitis in immunocompetent individual is not well established. We have obtained good result in this patient with a course of Ganciclovir following excision of the cyst. The rarity of cytomegaloviral upper esophageal involvement, its association with arytenoid cyst and the utility of antivirus in treatment of an immunocompetent host makes this case report unique and interesting.
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