释放给药系统的潜能:全面回顾制药学领域的制剂策略和技术

IF 0.3 Q4 PHARMACOLOGY & PHARMACY Current Drug Therapy Pub Date : 2023-11-22 DOI:10.2174/0115748855262877231114050949
Nitin Rajan, Shubham Kanaujiya
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引用次数: 0

摘要

近年来,为提高治疗效果、安全性和患者依从性而开发的创新给药系统在制药学领域取得了长足的发展。本文综述了最新的制剂技术和工艺,以改善药物分布并实现特定的治疗目标。本文全面总结了用于改善给药和提供特定治疗效果的最新制剂技术。文章讨论了各种给药方法,包括纳米颗粒、脂质体、胶束和树枝状分子,并探讨了纳米技术和生物技术在给药方面的应用。此外,论文还强调了靶向给药系统的重要性及其穿越生物屏障(包括血脑屏障和肿瘤微环境)的能力。这篇综述还探讨了药物递送系统的开发和商业化所面临的挑战,并提出了克服这些挑战的潜在解决方案。此外,文章还强调了计算建模和模拟在设计和优化给药系统中的作用。总之,这篇综述论文为制药学研究人员、科学家和从业人员提供了具有洞察力的信息,有助于创造新型给药系统,改善患者的治疗效果和生活质量。
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Unlocking the Potential of Drug Delivery Systems: A Comprehensive Review of Formulation Strategies and Technologies in the Field of Pharmaceutics
The creation of innovative drug delivery systems to enhance therapeutic effectiveness, safety, and patient compliance has resulted in considerable developments in pharmaceutics in recent years. The most recent formulation techniques and technologies are reviewed in this article to improve medication distribution and accomplish specific therapeutic goals. This article thoroughly summarizes the most recent formulation techniques and technologies used to enhance medication delivery and provide specific therapeutic effects. It discusses the variety of medication delivery methods, including nanoparticles, liposomes, micelles, and dendrimers, and explores the application of nanotechnology and biotechnology in drug delivery. Additionally, the paper emphasizes the significance of targeted drug delivery systems and their capacity to cross biological barriers including the blood-brain barrier and tumor microenvironment. The review also addresses the challenges faced in developing and commercializing drug delivery systems and suggests potential solutions to overcome them. Furthermore, the article emphasizes the role of computational modeling and simulation in designing and optimizing drug delivery systems. Overall, this review paper offers insightful information for pharmaceutics researchers, scientists, and practitioners that will help in the creation of novel drug delivery systems that improve patient outcomes and quality of life.
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来源期刊
Current Drug Therapy
Current Drug Therapy PHARMACOLOGY & PHARMACY-
CiteScore
1.30
自引率
0.00%
发文量
50
期刊介绍: Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.
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