洞察鲜为人知、来势汹汹的自身免疫性疾病真相

Selvi G
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摘要

自身免疫是一种被误导的免疫反应,当免疫系统变得混乱并攻击身体时就会发生。虽然自身免疫在我们大多数人身上都普遍存在,但它通常是无害的。这种免疫反应有时会导致多种疾病,即所谓的自身免疫性疾病。自身免疫性疾病始于从顺从性自身免疫发展到致病性自身免疫。这种发展受遗传和环境因素的影响,大多会休眠一段时间。在几乎没有生存选择的情况下,紧急情况突然复发。当 T 细胞或 B 细胞或两者在没有感染的情况下受到刺激时,就会导致免疫系统无法区分自身或非自身。这导致免疫细胞外流,从而破坏自身分子。这一事件的确切过程尚无定论,但迄今为止的研究预测,遗传、生境和感染一定是导致自身免疫反应异常激活的主要原因。
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An insight into the little-known, menacing facts of autoimmune disorder
Autoimmunity is a misguided immune response that occurs when the immune system becomes disorganized and attacks the body. While autoimmunity is prevalent to some extent in most of us, it is often harmless. This immune response can sometimes cause a wide range of diseases known as autoimmune diseases. Autoimmune diseases start when there is a development from submissive autoimmunity to pathogenic autoimmunity. This progression is influenced by both genetic and environmental factors and mostly remains dormant for a period. A sudden recurrence of emergencies occurs with few options for survival. When T or B-cells or both get stimulated in the absence of infection, it results in a state where the immune system is unable to distinguish between self or non-self. This results in the efflux of immune cells leading to the destruction of self-molecules. The exact process governing this event is still inconclusive, but the research done so far predicts that genetics, habitat, and infections must be major causes of abnormal activation of the autoimmune reaction.
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