Emulgel 及其上市配方概述

Sakshi Sanjay Patil., Pallavi Arjun Patil., Rutuja. R. Shah
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引用次数: 0

摘要

背景介绍凝胶剂是一种由乳液和凝胶混合而成的外用制剂。Emulgel 被认为是最重要的外用给药系统之一,因为它由凝胶和乳液两种释放控制系统组成。这种新型局部给药系统的主要目的是通过皮肤将疏水性药物送入全身循环。通过适当的统计设计,可以制备出不同等级的凝胶剂。它们具有各种有利的特性。因此,与其他外用给药系统相比,乳凝胶被认为是市场上最传统的系统。 目标:在本研究中,我们尝试制备大蒜油和鸦胆子油的润肤凝胶,以增强其局部给药效果。材料与方法:通过 pH 值、粘度、可剥离性、可挤出性、微生物检测等各种参数对乳胶配方进行表征。
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Overview on Emulgel and their marketed Formulations
Background: Emulgel is a topical preparation prepared by the mixture of an emulsion and a gel. Emulgel is considered as one of the most important topical delivery systems because it consists of two release control systems, i.e., a gel and an emulsion. The primary intention of this new topical delivery system is to deliver hydrophobic drugs into systemic circulation through the skin. By applying a suitable statistical design, different grades of emulgel can be prepared. There are various favorable properties. Therefore, emulgel is considered as the most conventional system available in the market over other topical drug delivery systems. Objectives: In the present work an attempt was made to prepare emulgel of garlic oil and ajwain oil for enhancing its topical delivery. Material and Method: Emulgel formulation was characterized by various parameters like pH, viscosity, spredability, Extrudability, microbiological Assay.
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