AMA AND EPIGENETICS MODIFIER IN THE MANIFESTATION OF VYADHI

We know that before treating any vyadhi, it is essential to analyse the sama or nirama stage of dosha. The changes brought by ama can be considered abnormal epigenetic modification. The internal pathology produced in the tissues, which is not visible but can be analysed through changes happening in the body, can be co-related to epigenetic changes. Epigenetics can be modified by different factors such as diet, lifestyle, behavioural changes, infection, pollution, etc., and the pathological changes in epigenetics brought by these factors can be considered as brought about by Ama, as the formation of Ama is also influenced by these physical, psychological and environmental factors. Hence, a conceptual study is done to analyse the relation between ama and epigenetics.