使用基于等离子体纳米传感器核酸检测系统的 AuNP-DNA 探针可视化检测肝癌基因中的 NQO 1 点突变

Shuhuang Chen
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引用次数: 0

摘要

等离子体纳米生物传感器是一种基于金属纳米粒子局部表面等离子体共振效应(LSPR)的光学生物传感器。本文主要介绍了利用AuNP-DNA作为核酸探针的等离子体纳米传感器核酸检测系统对肝癌表达相关基因NQO 1点突变进行可视化检测,并论述了等离子体纳米生物传感器与传统肝癌早期筛查方法相比的优势和广阔的应用前景,以及在肝癌形成或肝癌诊治领域及时治疗和提前预防发挥的重要作用。
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Visualized Detection of NQO 1 Point Mutations in the Liver Cancer Gene Using AuNP-DNA Probes based on a Plasmon Nanosensor Nucleic Acid Detection System
Plasmonic nanobiosensor is an optical biosensor based on the localized surface plasmon resonance effect (LSPR) of metal nanoparticles. This article mainly introduces the use of plasma nanosensor nucleic acid detection system of AuNP-DNA as nucleic acid probe for liver cancer expression related gene NQO 1 point mutation visual detection, and discusses the plasma nano biosensor compared with the traditional advantages of liver cancer early screening method and broad application prospects, and in the formation of liver cancer or liver cancer diagnosis and treatment in the field of timely treatment and prevention play an important role in advance.
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