体内评估胡桃果提取物的抗惊厥活性

Samruddhi Satish Vyawahare, Rajesh Mandade, Pranay Uplenchwar
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引用次数: 0

摘要

癫痫是一种慢性脑部疾病,影响着全世界的人们。大约 50-80% 的癫痫患者可以通过现有的抗癫痫药物得到控制。但这些药物无法有效控制约 10-20% 患者的癫痫发作。尽管新的抗惊厥药物正在研发中,但对癫痫的治疗仍然不足。本研究旨在调查雷公藤治疗癫痫发作的效果。在动物模型中,雷公藤果实提取物显示出抗惊厥活性。
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In-vivo Evaluation of Anticonvulsant activity of Juglans regia fruit extract
Epilepsy is a chronic disorder of the brain that affect people worldwide. Nearly about 50-80% of the patients with epilepsy are controlled with currently available antiepileptic drugs. But these drugs cannot able to control seizures effectively in about 10-20% of the patients. The treatment of epilepsy still remains inadequate even though new anticonvulsants are being developed. The present study was undertaken to investigate effect of J.regia in management of seizures.100 mg fruit extract was administered in seperate groups of animal. The J.regia fruit extract shows the anticonvulsant activity in animal model.
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