基孔肯雅病毒的细胞因子风暴：我们可以将其称为与基孔肯雅病相关的多系统炎症综合征吗？

IF 1.2 Q4 RHEUMATOLOGY Reumatologia Clinica Pub Date : 2024-04-01 DOI:10.1016/j.reuma.2023.10.003

Zoilo Morel , Tamara Martínez , Fernando Galeano , Judith Coronel , Lorena Quintero , Rolando Jimenez , Jorge Ayala , Sara Amarilla , Dolores Lovera , Celia Martínez de Cuellar

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引用次数: 0

摘要

巴拉圭目前正面临基孔肯雅病毒的新一轮爆发。本报告概述了经实时反转录聚合酶链反应证实的两例基孔肯雅病毒（CHIKV）严重感染病例。我们报告的病例是基孔肯雅病毒急性感染和多系统受累的患者，伴有发热、皮疹、腹痛、呕吐、心肌炎和冠状动脉异常，与 COVID-19 大流行期间与 SARS-CoV-2 相关的 MIS-C 中描述的病例非常相似。两名患者均接受了静脉注射免疫球蛋白和甲基强的松龙治疗，临床反应良好。在基孔肯雅病毒引起细胞因子风暴的情况下，我们是否可以称之为 "与基孔肯雅病毒相关的多系统炎症综合征"？

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Cytokine storm in Chikungunya: Can we call it multisystem inflammatory syndrome associated with Chikungunya?

Paraguay is currently facing a new outbreak of Chikungunya virus. This report summarizes two severe cases of Chikungunya (CHIKV) infection, confirmed by real-time reverse transcription polymerase chain reaction. We present the cases of patients with acute CHIKV infection and multisystem involvement, with fever, rash, abdominal pain, vomiting, myocarditis, and coronary artery anomalies, very similar to the cases described in MIS-C related to SARS-CoV-2 during the COVID-19 Pandemic. Both patients received IVIG and methylprednisolone, with good clinical response. In this setting of cytokine storm in Chikungunya, can we call it “Multisystem inflammatory syndrome associated with Chikungunya”?.

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来源期刊

Reumatologia Clinica RHEUMATOLOGY-

CiteScore

2.40

自引率

6.70%

发文量

105

审稿时长

54 days

期刊介绍： Una gran revista para cubrir eficazmente las necesidades de conocimientos en una patología de etiología, expresividad clínica y tratamiento tan amplios. Además es La Publicación Oficial de la Sociedad Española de Reumatología y del Colegio Mexicano de Reumatología y está incluida en los más prestigiosos índices de referencia en medicina.