{"title":"上唇单发环状神经瘤：病例报告","authors":"Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira","doi":"10.1016/j.ajoms.2023.11.009","DOIUrl":null,"url":null,"abstract":"<div><p><span><span>A solitary circumscribed neuroma is a benign </span>peripheral nerve tumor<span> with a predilection for the skin of the head and neck. Herein, we present a 73-year-old Japanese male with a solitary circumscribed neuroma of the upper lip. Histologically, the tumor comprised densely proliferating Schwann cells<span> and axons that formed fascicles. A thin perineural-derived fibrous capsule surrounded the tumor. Immunohistochemically, the tumor cells were positive for S-100, and neurofilaments indicated the presence of nerve fibers. Fibrous capsules were identified by epithelial membrane </span></span></span>antigen staining.</p></div>","PeriodicalId":45034,"journal":{"name":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","volume":"36 4","pages":"Pages 657-659"},"PeriodicalIF":0.4000,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Solitary circumscribed neuroma of the upper lip: A case report\",\"authors\":\"Kaori Shima, Phuong Thao Nguyen, Yudai Shimojukkoku, Yuka Kajiya, Tomonori Sasahira\",\"doi\":\"10.1016/j.ajoms.2023.11.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span>A solitary circumscribed neuroma is a benign </span>peripheral nerve tumor<span> with a predilection for the skin of the head and neck. Herein, we present a 73-year-old Japanese male with a solitary circumscribed neuroma of the upper lip. Histologically, the tumor comprised densely proliferating Schwann cells<span> and axons that formed fascicles. A thin perineural-derived fibrous capsule surrounded the tumor. Immunohistochemically, the tumor cells were positive for S-100, and neurofilaments indicated the presence of nerve fibers. Fibrous capsules were identified by epithelial membrane </span></span></span>antigen staining.</p></div>\",\"PeriodicalId\":45034,\"journal\":{\"name\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"volume\":\"36 4\",\"pages\":\"Pages 657-659\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2023-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Oral and Maxillofacial Surgery Medicine and Pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212555823002521\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Surgery Medicine and Pathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212555823002521","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Solitary circumscribed neuroma of the upper lip: A case report
A solitary circumscribed neuroma is a benign peripheral nerve tumor with a predilection for the skin of the head and neck. Herein, we present a 73-year-old Japanese male with a solitary circumscribed neuroma of the upper lip. Histologically, the tumor comprised densely proliferating Schwann cells and axons that formed fascicles. A thin perineural-derived fibrous capsule surrounded the tumor. Immunohistochemically, the tumor cells were positive for S-100, and neurofilaments indicated the presence of nerve fibers. Fibrous capsules were identified by epithelial membrane antigen staining.
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