作为多学科问题的 COVID-19:对生殖健康的影响(文献综述)

S.M. Turyanytsia, N.O. Loya, O.O. Korchynska, A.V. Sabovа, V.V. Malyar
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摘要

COVID-19 是一种由严重急性呼吸系统综合征冠状病毒-2(SARS-CoV-2)引起的传染病。世卫组织于 2020 年 3 月 11 日宣布 COVID-19 为全球大流行病。毫无疑问,没有人会否认传染病学在不同年龄组的所有疾病中占据着重要地位。冠状病毒感染的持续大流行就是生动的证明。因此,这种疾病一直在寻找能让它在与病原体的斗争中占据优势的手段。近年来的研究表明,COVID-19 不仅会影响呼吸系统、循环系统和神经系统,还会影响生殖系统,尤其是女性生殖系统。COVID-19 的流行引发了科学界的争论,争论的焦点是感染 COVID-19 的女性发生月经变化的风险,如月经持续时间、频率、规律性和经量的紊乱(包括出血和凝血增加)、痛经严重程度的增加以及经前综合征。然而,关于 COVID-19 对生殖健康的影响,目前还没有足够的数据或信息。COVID-19 大流行病对妇女生殖健康的潜在负面影响问题在妇科医生的临床实践中正变得越来越重要。必须强调的是,妇科医生必须开展高质量的工作,包括早期诊断生殖系统疾病,进行适当的诊断和治疗,以防止卵巢-月经周期紊乱、不孕和流产等并发症的发生。因此,进一步研究育龄妇女感染冠状病毒的长期后果至关重要。
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COVID-19 as a multidisciplinary problem: impact on reproductive health (Literature review)
COVID-19 is an infectious disease which is caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). According to the WHO, on March 11, 2020, COVID-19 was declared a global pandemic. Undoubtedly, no one will deny that infectious pathology occupied and is occupying a significant place among all diseases of different age groups. The ongoing pandemic of coronavirus infection is a vivid proof of this.There is probably no such person in the world who would never “has his own little war” with infectious pathogens. Therefore, the disease is constantly looking for means that would give it an advantage in the fight against pathogens. Research in recent years indicates that COVID-19 affects not only the respiratory, circulatory and nervous systems, but also the reproductive system, in particular the female one.The article is devoted to a review of scientific publications that describe the impact of COVID-19 on women’s reproductive health. The COVID-19 pandemic has sparked debate in the scientific community focusing on the risk of menstrual changes in women with COVID-19, such as disorders in the duration, frequency, regularity, and volume of menstruation (including increased bleeding and clotting), increased severity of dysmenorrhea, and premenstrual syndrome. However, there is not enough data or information about the impact of COVID-19 on reproductive health.The problem of remote potential negative impact of the COVID-19 pandemic on women’s reproductive health is becoming more and more relevant in the practice of gynecologists. It is important to emphasize the need for high-quality work of gynecologists, which includes early diagnosis of reproductive disorders, adequate diagnosis and treatment in order to prevent complications in case of ovarian-menstrual cycle disorders, infertility and miscarriage.Unfortunately, to date there are no unambiguous data on the impact of SARS-CoV-2 on the reproductive system. Therefore, further research into the long-term consequences of the transferred coronavirus infection in women of reproductive age is critically important.
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