不同强度的运动对年轻雄性 Wistar 大鼠骨结构的影响

Filiani Natalia Salim, H. Goenawan, Faysal Kastella, Ronny Lesmana, Leonardo Lubis
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引用次数: 0

摘要

许多青少年体育活动不足。从小进行有规律的体育锻炼可以增强体质和健康。应鼓励儿童和青少年经常锻炼和健康饮食,以预防成年和老年后的各种疾病,如骨质疏松症和骨折。运动时,需要根据每个人的能力量身定制运动处方。每个人的年龄、生理机能、遗传、经济状况、既往合并症等因素不同,运动强度也不同。目前还没有标准的运动处方被证明可以提高青少年的骨质密度。根据上述描述,我们进行了一项关于提供不同强度运动及其对骨骼形态和密度影响的研究。该研究将 15-16 周大的雄性 Wistar 大鼠(体重 ± 250-350 克;n = 20)分为 4 组,即对照组、低强度运动组、中等强度运动组和高强度运动组。所有组均接受为期 8 周的干预。然后,大鼠被处死并分离股骨。检查股骨重量和股骨长度。使用 X 光检查骨密度,并通过统计检验进行计算。研究在 Padjadjaran 大学的中央实验室进行。高强度运动组与对照组和低强度运动组的股骨重量存在明显差异(P 0.05)。与对照组和低强度运动组相比,中等强度和高强度运动明显增加了股骨长度(P 0.05)。中度和高强度运动组的骨密度更高(P 0.05)。从骨形态分析的显著性以及与低强度运动相比更高的骨密度可以看出,中高强度运动可以增强骨骼健康。
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Effects of Different Intensity Exercises On Bone Structure of Young Male Wistar Rats
Many adolescents have insufficient physical activity. Regular physical activity from young age can improve health and fitness. Getting regular exercise and eating healthy diet should be encouraged among kids and teenagers to prevent various diseases in adulthood and old age, such as osteoporosis and fractures. When exercising, a prescription is needed that is tailored to each individual abilities. The intensity of exercise will be different for each individual in accordance with their age, physiological function, genetics, economic status, and previous comorbid diseases. There is no standardised exercise prescription proven to increase bone mineral density in adolescents. Based on the above description, a study was conducted on the provision of different intensity exercise and its effect on bone morphology and density. In this study, male Wistar rats, aged 15–16 weeks (body weight ± 250-350 grams; n = 20), were split into 4 groups, namely control group, low intensity exercise group, moderate intensity exercise group, and high intensity exercise group. All groups were receiving intervention for 8 weeks. Then, the rats were sacrificed and the femoral bones were isolated. Femur weight and femur length was checked. Bone density was examined using X-Ray and calculated by statistical tests. Research was conducted in the Central Laboratory, Universitas Padjadjaran. There were significant differences of femur weight between high intensity exercise group and control and low intensity exercise groups (p 0.05). Moderate and high intensity exercises significantly increased femur length as opposed to control and low intensity exercise groups (p 0.05). Bone density was higher in moderate and high intensity exercise groups (p 0.05). Moderate to high intensity exercise can increase bone health, seen from significances of bone morphology analysis and a higher density compared to low intensity exercise.
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