巴库市多发性硬化症的流行病学指标

A.I. Guliyeva, R. Shiraliyeva, R.L. Hasanov, Z.M. Sadykhova
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摘要

导言:多发性硬化症(MS)是一种中枢神经系统自身免疫性疾病。多发性硬化症(MS)是一种中枢神经系统自身免疫性疾病,在患有神经系统疾病的年轻人中致残率排名第二。目前,阿塞拜疆尚未对多发性硬化症的流行病学进行大规模研究。本研究的目的是对巴库市居民中多发性硬化症的流行率和发病率进行研究。材料和方法。研究材料为 559 名患者。其中女性 392 人(占 70%),男性 167 人(占 30%)。多发性硬化症的最终诊断依据 2010 年麦克唐纳标准。结果显示2013年,多发性硬化症的发病率为每10万人中有10.2名患者。从 2014 年到 2019 年,患病率从每 10 万人中 12.3 例增加到 23.3 例。从统计学角度看,多发性硬化症的男女患病率有显著差异,为 2.3:1。从 2013 年到 2020 年,多发性硬化症的发病率保持相对稳定,为每 10 万人 2.1-2.9 例。在 2013-2019 年期间,女性的发病率逐年上升,从每 10 万人 2.7 例上升至 3.7 例,而男性的发病率则呈下降趋势,从每 10 万人 2.1 例下降至 0.9 例。多发性硬化症在 20-29 岁和 30-39 岁年龄段的发病率最高。结论根据多发性硬化症的发病率,巴库市属于中等风险地区。从 2013 年到 2019 年,女性多发性硬化症发病率的增长速度高于男性。巴库多发性硬化症的发病率相对稳定,为每 10 万人 2.1-2.9 例。在所有研究年份中,多发性硬化症的发病率主要集中在 20 至 40 岁的人群中。
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EPIDEMIOLOGICAL INDICATORS OF MULTIPLE SCLEROSIS IN THE CITY OF BAKU
Introduction. Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, which ranks the second place according to the frequency of disability among young people with neurological disorders. At present, there has not been made any large-scale epidemiological study on the epidemiology of MS in Azerbaijan. The purpose of the research is to study the prevalence and incidence of MS among residents of Baku city. Material and Methods. The material of the research was 559 patients. There were 392 (70%) females and 167 (30%) males. The final diagnosis of MS was made according to the 2010 McDonald criteria. Results. The prevalence of MS was 10.2 patients per 100000 people in 2013. From 2014 to 2019, there was an increase in prevalence from 12.3 to 23.3/100000. The prevalence of MS among men and women was statistically significantly different by statics and came to 2.3:1. The incidence of MS from 2013 to 2020 remained relatively stable at the rate of 2.1-2.9 per 100,000 people. The incidence rate of women in the period of 2013-2019 increased over the years from 2.7 to 3.7, as to men it had a downward trend from 2.1 to 0.9 per 100,000 people. The incidence of MS had the highest representation in the age groups of 20-29 and 30- 39. Conclusion. According to the prevalence of MS, the city of Baku corresponds to the geographic zones of medium risk. The increase in the prevalence of MS from 2013 to 2019 with women occurs at a higher rate than with men. The incidence rate of MS in Baku remains relatively stable at 2.1-2.9 patients per 100,000 people. The incidence of MS in the number of people aged from 20 to 40 prevails in all the years studied.
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