Antibiotic effectiveness against Staphylococcus aureus isolated from clinical cases in babylon hospitals

Background: Staphylococcus aureus, especially those that are multidrug-resistant, constitute a public health problem worldwide. It has been represented as the most common causative agent of skin infections, wound infections, and bacteremia. Objective: The purpose of the current study was to determine the incidence of S. aureus antibiotic resistance through bacteria collection from various clinical locations in a number of hospitals in the Babylon province. Materials and Methods: During the research, 429 clinical samples were collected from hospitals in the Babylon Health Directorate between July 2022 and February 2023. The samples were cultured in routine selective media, and the bacterial isolates were found according to different testing biochemically. The disc diffusion method was used in an antibacterial sensitivity test. Results: Of 429 different specimens, 284 (66.2%) showed bacterial growth. After using manual methods to identify species, 171 (60.21%) of 284 isolates are Staphylococcus spp. From 171 Staph species, 61 (35.67%) were S. aureus. These isolates award a maximum rate of sensitivity to nitrofurantoin (90%) and chloramphenicol (95%) and showed a maximum ratio of resistance to penicillin (91%) and cefoxitin (85%). Conclusion: High prevalence of S. aureus 61 (35.67%) from 171 Staphylococcus species. Antibiotics indicated a high ratio of sensitivity to nitrofurantoin (90%) and chloramphenicol (95%) and indicated a high ratio of resistance to penicillin (91%) and cefoxitin (85%). The purpose of the current study was to determine the incidence S. aureus antibiotic resistance through bacteria collection from various clinical locations in a number of hospitals in the Babylon province.