综合电子健康记录数据中作为确诊长 COVID-19 综合征风险因素的既存精神疾病。

IF 2.9 3区医学 Q2 PSYCHIATRY Psychosomatic Medicine Pub Date : 2024-04-01 Epub Date: 2024-01-08 DOI:10.1097/PSY.0000000000001280

Lukas Bobak, Ian Dorney, Alexsandra Kovacevich, Brian Barnett, David C Kaelber

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引用次数: 0

摘要

目的调查感染 SARS-CoV-2 并已患有精神疾病的患者与未患有精神疾病的患者被诊断为长期 COVID 的频率：TriNetX Analytics 平台是一个电子病历 (EHR) 研究聚合网络，包含 9000 多万患者的去标识化电子病历数据。根据患者原有的精神状况对其进行分层，并记录和报告新诊断的长COVID作为主要结果：结果：在 1,180,948 名曾被诊断为 COVID-19 的患者中，有 17,990 名（1.52%）患者根据新实施的 ICD-10 编码 "U09：COVID-19 后病情 "被诊断为长 COVID。经过倾向得分匹配后，感染前已存在任何精神疾病诊断的患者在感染后 180 天内被确诊为长 COVID 的患病率是未存在精神疾病诊断的患者的 1.52 倍（95% CI：1.47,1.58）。确诊为焦虑症（RR：1.64，95% CI：1.57,1.71）、情绪障碍（RR：1.65，95% CI：1.57,1.72）、双相情感障碍（RR：1.37，95% CI：1.21,1.54）、重度抑郁障碍（RR：1.69，95% CI：1.56,1.83）、精神病性障碍（RR：1.23，95%：1.06,1.44）和药物使用障碍（RR:1.28，95% CI：1.22,1.36）与诊断时无既往精神病的患者相比，诊断为长期 COVID 的风险更高：结论：在感染 COVID-19 后，原有的多种精神疾病与被诊断为长期 COVID 的风险增加有关。

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Preexisting Psychiatric Conditions as Risk Factors for Diagnosed Long COVID-19 Syndrome Within Aggregated Electronic Health Record Data.

Objective: This study aimed to investigate the frequency of long COVID diagnosis among patients infected with severe acute respiratory syndrome coronavirus 2 with preexisting psychiatric conditions versus those without preexisting psychiatric conditions.

Methods: The TriNetX Analytics platform, an aggregated electronic health record research network containing the deidentified electronic health record data of more than 90 million patients, was queried for patients who were diagnosed with COVID-19 infection based on International Classifications of Disease, Tenth Revision codes. Patients were stratified based on their preexisting psychiatric conditions, and new diagnoses of long COVID were recorded and reported as the primary outcome.

Results: Among 1,180,948 patients previously diagnosed with COVID-19, 17,990 patients (1.52%) were diagnosed with long COVID based on the newly implemented International Classifications of Disease, Tenth Revision code "U09: post-COVID-19 condition." After propensity score matching, patients with any preexisting psychiatric diagnosis had a 1.52 (95% confidence interval [CI] = 1.47-1.58) times greater prevalence of diagnosed long COVID within 180 days of infection than patients without preexisting psychiatric diagnoses. Patients with diagnosed anxiety disorders (relative risk [RR] = 1.64; 95% CI = 1.57-1.71), mood disorders (RR = 1.65; 95% CI = 1.57-1.72), bipolar disorder (RR = 1.37; 95% CI = 1.21-1.54), major depressive disorder (RR = 1.69; 95% CI = 1.56-1.83), psychotic disorders (RR = 1.23; 95% CI = 1.06-1.44), and substance use disorders (RR = 1.28; 95% CI = 1.22-1.36) had higher risks for long COVID diagnoses when compared with patients without preexisting psychiatric illness at the time of diagnosis.

Conclusions: Multiple preexisting psychiatric diagnoses are associated with an increased risk of being diagnosed with long COVID after COVID-19 infection.

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来源期刊

Psychosomatic Medicine 医学-精神病学

CiteScore

5.10

自引率

0.00%

发文量

258

审稿时长

4-8 weeks

期刊介绍： Psychosomatic Medicine is the official peer-reviewed journal of the American Psychosomatic Society. The journal publishes experimental, clinical, and epidemiological studies on the role of psychological and social factors in the biological and behavioral processes relevant to health and disease. Psychosomatic Medicine is an interdisciplinary peer-reviewed journal devoted to high-quality science on biobehavioral mechanisms, brain-behavior interactions relevant to physical and mental disorders, as well as interventions in clinical and public health settings. Psychosomatic Medicine was founded in 1939 and publishes interdisciplinary research articles relevant to medicine, psychiatry, psychology, and other health-related disciplines. The print journal is published nine times a year; most articles are published online ahead of print. Supplementary issues may contain reports of conferences at which original research was presented in areas relevant to the psychosomatic and behavioral medicine.