用电化学和光学生物传感器检测肌酐的趋势

IF 7.5 Q1 CHEMISTRY, PHYSICAL Applied Surface Science Advances Pub Date : 2024-01-10 DOI:10.1016/j.apsadv.2023.100567
Radhika Babasaheb Jadhav, Tejaswini Patil, Arpita Pandey Tiwari
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引用次数: 0

摘要

肌酐是肌肉中磷酸肌酸的副产品,为肌肉组织提供能量。临床上必须评估尿液和血液中的肌酐水平,因为它是肾脏、肌肉和甲状腺功能的指标。护理点医疗诊断研发是最具创新性的探索性研究。肌酐的测定可通过几种传统方法实现,如比色法、分光光度法和色谱法。这些方法虽然灵敏度高、选择性强,但也存在一些缺点,如分析时间长、需要对样品进行预处理、仪器昂贵和需要专业人员。相比之下,传感器和生物传感器提供了快速、用户友好、经济高效和高灵敏度的替代方法,是解决这些局限性的有利方案。这篇综述文章介绍了使用电化学和光学生物传感器检测肌酐的最新趋势,以及生物传感器的优缺点。这篇综述强调了肌酐的广泛检测范围,并探讨了生物传感器与家庭监测系统的商业化问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Trends in sensing of creatinine by electrochemical and optical biosensors

Creatinine is the by-product of creatine phosphate within the muscle, supplying energy to the muscle tissues. It is imperative to clinically assess creatinine levels in both urine and blood as it serves as an indicator of renal, muscle, and thyroid functionality. The point-of-care medical diagnostic research and development is the most innovative form of exploratory research. The determination of creatinine can be achieved through several traditional methods such as colorimetric, spectrophotometric and chromatographic techniques. Although these method offers high sensitivity and selectivity, they are accompanied by drawback such as long analysis time, the need for sample pre-treatment, expensive instruments and skilled personnel. In contrast, sensors and biosensors present a favourable solution to these limitations as they offer rapid, user-friendly, cost effective and highly sensitive alternatives. This review article describe recent trends in creatinine detection by using electrochemical and optical biosensors, advantages and disadvantages of biosensors. This review highlights the wide detection range of creatinine and explore the commercialization aspects of biosensors with in home monitoring system.

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CiteScore
8.10
自引率
1.60%
发文量
128
审稿时长
66 days
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