Christopher M Warren, Shruti Sehgal, Scott H Sicherer, Ruchi S Gupta
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引用次数: 0
摘要
综述的目的:食物过敏是一种由免疫介导的复杂疾病,是全球日益关注的健康问题的根源。本综述旨在对不同人群中儿童和成人的食物过敏(FA)负担进行最新总结,重点关注过去 5 年的研究结果:食物过敏影响着越来越多的全球居民,尤其是那些居住在高收入、工业化地区的居民。此外,越来越多的流行病学证据表明,非 IgE 介导的 FAs(如食物蛋白诱发的小肠结肠炎综合征)对人群健康造成的负担可能也高于之前的报道。肠炎是一种影响全球婴儿、儿童和成人的复杂病症。如果不快速推进和广泛实施有效的 FA 预防和治疗干预措施,IgE 和非 IgE 介导的 FA 对人口健康造成的负担可能会越来越大。为了更好地了解和减轻这些过敏性疾病的负担,需要在国家和全球范围内开展系统的流行病学研究活动。
Epidemiology and the Growing Epidemic of Food Allergy in Children and Adults Across the Globe.
Purpose of review: Food allergies are immune-mediated, complex disorders, which are the source of increasing health concern worldwide. The goal of this review is to present an updated summary of the food allergy (FA) burden among children and adults across different populations, focusing on research from the past 5 years.
Recent findings: FAs impact a growing number of global residents-particularly those residing in higher-income, industrialized regions. Moreover, growing epidemiologic evidence suggests that the population health burden of non-IgE-mediated FAs, such as food protein-induced enterocolitis syndrome, may also be higher than previously reported. FA is a complex trait that impacts infants, children, as well as adults across the globe. The population health burden of both IgE- and non-IgE-mediated FAs is likely to grow in the absence of rapid advances and widespread implementation of effective FA prevention and treatment interventions. Systematic epidemiological research initiatives are needed, both nationally and globally, to better understand and reduce the burden of these allergic diseases.
期刊介绍:
The aim of Current Allergy and Asthma Reports is to systematically provide the views of highly selected experts on current advances in the fields of allergy and asthma and highlight the most important papers recently published. All reviews are intended to facilitate the understanding of new advances in science for better diagnosis, treatment, and prevention of allergy and asthma.
We accomplish this aim by appointing international experts in major subject areas across the discipline to review select topics emphasizing recent developments and highlighting important new papers and emerging concepts. We also provide commentaries from well-known figures in the field, and an Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. Over a one- to two-year period, readers are updated on all the major advances in allergy and asthma.