心力衰竭患者限钠限液的证据现状。

IF 5.6 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Progress in cardiovascular diseases Pub Date : 2024-01-01 DOI:10.1016/j.pcad.2024.01.004
Eloisa Colin-Ramirez , Joanne Arcand , Clara Saldarriaga , Justin A. Ezekowitz
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引用次数: 0

摘要

心力衰竭领域的疗法不断发展,包括药物和器械疗法。现在有大量随机试验数据表明,饮食限钠并不能减少临床事件,而且临床试验结果存在公认的异质性。应考虑对部分而非所有患者进行饮食限钠,其目的不同于临床结果,而是为了提高潜在的生活质量。此外,液体限制曾是临床实践的主流,但并未显示出对住院或非卧床护理环境中的患者有任何额外的益处,因此在临床实践中应谨慎使用(如果有的话)。该领域还需要进一步的发展和临床试验,以更好地确定哪些患者可能从这些成本较低的干预措施中获益或受到损害,未来的研究应侧重于大规模、高质量的临床试验,而不是以观察数据来推动临床实践。
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The current state of evidence for sodium and fluid restriction in heart failure

The field of heart failure has evolved in terms of the therapies that are available including pharmaceutical and device therapies. There is now substantial randomized trial data to indicate that dietary sodium restriction does not provide the reduction in clinical events with accepted heterogeneity in the clinical trial results. Dietary sodium restriction should be considered for some but not all patients and with different objectives than clinical outcomes but instead for potential quality of life benefit. In addition, fluid restriction, once the mainstay of clinical practice, has not shown to be of any additional benefit for patients in hospital or in the ambulatory care setting and therefore should be considered to be used cautiously (if at all) in clinical practice. Further developments and clinical trials are needed in this area to better identify patients who may benefit or have harm from these lower cost interventions and future research should focus on large scale, high quality, clinical trials rather than observational data to drive clinical practice.

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来源期刊
Progress in cardiovascular diseases
Progress in cardiovascular diseases 医学-心血管系统
CiteScore
10.90
自引率
6.60%
发文量
98
审稿时长
7 days
期刊介绍: Progress in Cardiovascular Diseases provides comprehensive coverage of a single topic related to heart and circulatory disorders in each issue. Some issues include special articles, definitive reviews that capture the state of the art in the management of particular clinical problems in cardiology.
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