Patient-Reported Outcome Measures (PROMs) in Neurology for Web 3.0 and mHealth: A Conceptual Framework

According to 2019 WHO data, neurological conditions contribute to 1503.39 disability-adjusted life years (DALYs) per 100,000 population. Approximately 57% of office-based physicians use EHR systems and the natural place to incorporate standardized ePRO is into EHR. However, implementing patient-reported outcomes (PROs) for neurological conditions is challenging because many patients are elderly, have comorbidities, and experience cognitive impairment. As healthcare digitization increases, we propose a framework for easily customizable electronic PROs (ePROMs) in neurology. The framework requires implementation of technological standards, including governance plans, integration, and reporting workflows. It consists of four steps: developing an ePRO questionnaire, making ePRO mobile-compatible and user-friendly, building consensus around ePRO, and validating ePRO. It is important to involve all stakeholders in the ePRO development process and continuously monitor and evaluate progress in real-time to sustain ePRO tools over time.