Olga Ulyanova, N. A. Ermolenko, I. Banin, Vera V. Belinskaya, T. Dutova, Arkady V. Kulikov, Nadezhda P. Golovina
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引用次数: 0
摘要
在感染中枢神经系统(CNS)的细菌中,单核细胞增生李斯特菌(一种细胞内细菌,Lm)是对人类和动物最致命的细菌之一。李斯特菌病主要影响家畜和农畜(猪、小牛和大牛、马、兔子,很少影响猫和狗),以及家禽和装饰用鸟类(鹅、鸡、鸭、火鸡、鸽子、鹦鹉和金丝雀)。在鱼类和海产品(虾)中也能检测到 Lm。Lm 的传染源是动物,在这些动物中,疾病以表现型、消退型和无症状型的形式出现,并过渡到长期携带。这种病原体在世界各地的食品中都有发现,大多数情况下是在食用受污染的食物时感染的。胚胎、新生儿、老年人、免疫缺陷患者和慢性病患者尤其容易患病。Lm 可导致颅内出血、脑膜炎、脑膜脑炎(ME)和菱形脑炎。在这项工作中,我们介绍了自己在新型冠状病毒(COVID-19)感染的背景下,对一名 40 岁以上患者发生严重李斯特菌病 ME 的临床观察结果。
LISTERIOZNYY MENINGOENCEPHALIT ON THE PHONE OF THE NEW CORONAVIRUS INFANTRY. CLINICAL CASE
Among the bacteria that infect the central nervous system (CNS), Listeria monocytogenes (a facultative intracellular bacterium, Lm) is one of the most deadly for humans and animals. Listeriosis affects domestic and agricultural animals (pigs, small and large cattle, horses, rabbits, rarely cats and dogs), as well as domestic and decorative birds (geese, chickens, ducks, turkeys, pigeons, parrots and canaries). Lm can be detected in fish and seafood (shrimp). The source of infection with Lm are animals in which the disease proceeds in the form of manifest, erased and asymptomatic forms with a transition to long-term carriage. This pathogen is found all over the world in food products and in most cases infection occurs when eating contaminated food. Embryos, newborns, elderly people and persons with immunodeficiency states and chronic diseases are especially prone to disease. Lm is capable of causing intracranial hemorrhage, meningitis, meningoencephalitis (ME) and rhombencephalitis. In this work, we present our own clinical observation of the development of severe listeriosis ME in a patient older than 40 years on the background of the novel coronavirus infection (COVID-19).