鼻腔阻塞:病理生理学概述和犀牛(鼻)成形术的临床相关术前计划。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-06-01 Epub Date: 2024-01-15 DOI:10.1055/s-0043-1777850
Simon Snoeks, Enrique Velasco, Karel Talavera, Peter W Hellings
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引用次数: 0

摘要

鼻呼吸障碍是一种非常普遍且令人烦恼的症状,会影响日常功能和/或睡眠质量。面对寻求鼻整形手术的患者,外科医生需要仔细分析患者术前的鼻腔呼吸能力,并预测鼻(隔)成形术对鼻腔呼吸的积极甚至消极影响。鉴于鼻呼吸不畅的主观感觉与鼻流量和鼻阻力的客观测量结果之间缺乏相关性,因此必须对鼻阻塞所涉及的所有解剖、粘膜和感觉机制进行严格的临床评估。事实上,鼻腔粘膜上的热感、机械感和化学感受器、气流和呼吸动力学都可能对鼻腔呼吸能力的整体感知做出贡献。在这篇综述中,我们概述了决定鼻腔呼吸不达标的因素,包括可用于评估鼻腔流量和鼻腔阻力的不同诊断和实验测试,以及目前我们对个体患者鼻腔呼吸问题认识的局限性。文中还包括鼻阻塞术前或诊断工作的算法,可作为临床医生处理寻求鼻部手术患者的指南。
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Nasal Obstruction: Overview of Pathophysiology and Presentation of a Clinically Relevant Preoperative Plan for Rhino(Septo)plasty.

Impairment of nasal breathing is a highly prevalent and bothersome symptom that affects daily functioning and/or sleep quality. Those surgeons dealing with patients seeking rhinoplasty need to carefully analyze the preoperative nasal breathing capacity and predict the positive or even negative impact of rhino(septo)plasty on nasal breathing. Given the lack of correlation between the subjective feeling of suboptimal nasal breathing and the objective measurements of nasal flow and nasal resistance, a critical and mainly clinical evaluation of all anatomical, mucosal, and sensory mechanisms involved in nasal obstruction is mandatory. Indeed, thermo-, mechano-, and chemosensory receptors on the nasal mucosa, airflow, and respiratory dynamics might all contribute to the overall perception of nasal breathing capacity. In this review, we provide an overview of the factors determining suboptimal nasal breathing including different diagnostic and experimental tests that can be performed to evaluate nasal flow and nasal resistance and current limitations in our understanding of the problem of nasal breathing in an individual patient. An algorithm for the preoperative or diagnostic workup for nasal obstruction is included that might be useful as a guide for clinicians dealing with patients seeking nose surgery.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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