痴呆症临床前期和前驱期神经精神症状的识别：开发轻度行为障碍筛查测试。

IF 3.2 2区心理学 Q1 PSYCHOLOGY, MULTIDISCIPLINARY Psicothema Pub Date : 2024-01-01 DOI:10.7334/psicothema2023.40

Cristóbal Pereira-Abello, Marcelino Cuesta-Izquierdo, Laudino López-Álvarez, Alfonso García-Viejo

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引用次数: 0

摘要

背景：神经精神症状（NPS）是神经退行性疾病的一个精神病理层面，包括人格改变、行为障碍以及食欲或睡眠等基本功能的改变。本研究的目的是根据 ISTAART 的轻度行为损害（MBI）标准，构建并验证一种筛查测试，以识别这些在临床前和前驱阶段与神经退行性病变相关的 NPS：样本包括 206 名 55 岁以上的受试者（117 名认知健康，89 名患有轻度认知障碍）。69%为女性，平均年龄为 77 岁（SD = 10.58）：新量表由 19 个项目组成，呈一维结构。信度非常好（α = .94 和Ω = .97），与 MBI-C 测试（r = .88）和 NPI-Q 测试（r = .82）有收敛效度的证据。此外，该量表还具有良好的灵敏度（.88）和特异性（.80）：该量表可对 DCoL 中的 NPS 进行评估。它具有良好的心理测量特性，是早期诊断神经退行性病变的有用工具。

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Identification of Neuropsychiatric Symptoms in Preclinical and Prodromal Stages in Dementias: Development of a Screening Test for Mild Behavioral Impairment.

Background: Neuropsychiatric symptoms (NPS) are a psychopathological dimension of neurodegenerative diseases, consisting of personality changes, behavioral disorders, and alterations in basic functions such as appetite or sleep, among others. The aim of this study was the construction and validation of a screening test to identify these NPS associated with neurodegenerative pathologies in preclinical and prodromal stages, based on the ISTAART criteria for Mild Behavioral Impairment (MBI).

Method: The sample consisted of 206 subjects over 55 years old (117 cognitively healthy, 89 with Mild Cognitive Impairment). 69% were women, the mean age was 77 years ( SD = 10.58).

Results: The new scale consists of 19 items and exhibited a one-dimensional structure. Confidence was excellent (α = .94 and Ω = .97) and there was evidence of convergent validity with the MBI-C test ( r = .88) and the NPI-Q ( r = .82). In addition, the scale demonstrated good sensitivity (.88) and specificity (.80).

Conclusions: The scale allows evaluation of NPS in DCoL. It exhibits good psychometric properties and makes a useful tool in early diagnosis of neurodegenerative pathologies.

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来源期刊

Psicothema PSYCHOLOGY, MULTIDISCIPLINARY-

CiteScore

6.50

自引率

16.70%

发文量

审稿时长

24 weeks

期刊介绍： La revista Psicothema fue fundada en Asturias en 1989 y está editada conjuntamente por la Facultad y el Departamento de Psicología de la Universidad de Oviedo y el Colegio Oficial de Psicólogos del Principado de Asturias. Publica cuatro números al año. Se admiten trabajos tanto de investigación básica como aplicada, pertenecientes a cualquier ámbito de la Psicología, que previamente a su publicación son evaluados anónimamente por revisores externos. Psicothema está incluida en las bases de datos nacionales e internacionales más relevantes, entre las que cabe destacar Psychological Abstracts, Current Contents y MEDLINE/Index Medicus, entre otras. Además, figura en las listas de Factor de Impacto del Journal Citation Reports. Psicothema es una revista abierta a cualquier enfoque u orientación psicológica que venga avalada por la fuerza de los datos y los argumentos, y en la que encuentran acomodo todos los autores que sean capaces de convencer a los revisores de que sus manuscritos tienen la calidad para ser publicados. Psicothema es una revista de acceso abierto lo que significa que todo el contenido está a disposición de cualquier usuario o institución sin cargo alguno. Los usuarios pueden leer, descargar, copiar, distribuir, imprimir, buscar, o realizar enlaces a los textos completos de esta revista sin pedir permiso previo al editor o al autor, siempre y cuando la fuente original sea referenciada. Para acervos y repositorios, se prefiere que la cobertura se realice mediante enlaces a la propia web de Psicothema. Nos parece que una apuesta decidida por la calidad es el mejor modo de servir a nuestros lectores, cuyas sugerencias siempre serán bienvenidas.