环境产生的机会性细菌病原体在火星条件下的存活率:人类火星任务是否需要关注?

IF 3.5 3区 物理与天体物理 Q2 ASTRONOMY & ASTROPHYSICS Astrobiology Pub Date : 2024-01-01 DOI:10.1089/ast.2023.0057
Tommaso Zaccaria, Marien I de Jonge, Jorge Domínguez-Andrés, Mihai G Netea, Kristina Beblo-Vranesevic, Petra Rettberg
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引用次数: 0

摘要

在前往太阳系新天体的太空旅行中,宇航员的健康是飞行任务规划中的一个关键因素。尽管采取了清洁和净化措施,但在航天器上还是发现了或将会发现来自地球的微生物。这引发了对人类安全和行星保护的担忧,特别是如果这些微生物能够进化并适应新环境的话。在这项研究中,我们考察了与临床相关的非苛氧菌(来源于环境的伯克霍尔德氏菌、肺炎克雷伯氏菌、铜绿假单胞菌和肉豆蔻沙雷氏菌)对模拟火星条件的耐受性。我们的研究表明,在存在高氯酸盐、干燥条件下、暴露于紫外线辐射以及暴露于火星大气成分和压力的情况下,这些菌种的生长和存活率会发生变化。此外,我们的研究结果表明,在生长介质中添加火星流石模拟物可促进生长。今后还需要进行更多的研究,以检查这些物种在暴露于火星条件下的感染性、致病性和毒力的潜在变化。
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Survival of Environment-Derived Opportunistic Bacterial Pathogens to Martian Conditions: Is There a Concern for Human Missions to Mars?

The health of astronauts during space travel to new celestial bodies in the Solar System is a critical factor in the planning of a mission. Despite cleaning and decontamination protocols, microorganisms from the Earth have been and will be identified on spacecraft. This raises concerns for human safety and planetary protection, especially if these microorganisms can evolve and adapt to the new environment. In this study, we examined the tolerance of clinically relevant nonfastidious bacterial species that originate from environmental sources (Burkholderia cepacia, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Serratia marcescens) to simulated martian conditions. Our research showed changes in growth and survival of these species in the presence of perchlorates, under desiccating conditions, exposure to ultraviolet radiation, and exposure to martian atmospheric composition and pressure. In addition, our results demonstrate that growth was enhanced by the addition of a martian regolith simulant to the growth media. Additional future research is warranted to examine potential changes in the infectivity, pathogenicity, and virulence of these species with exposure to martian conditions.

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来源期刊
Astrobiology
Astrobiology 生物-地球科学综合
CiteScore
7.70
自引率
11.90%
发文量
100
审稿时长
3 months
期刊介绍: Astrobiology is the most-cited peer-reviewed journal dedicated to the understanding of life''s origin, evolution, and distribution in the universe, with a focus on new findings and discoveries from interplanetary exploration and laboratory research. Astrobiology coverage includes: Astrophysics; Astropaleontology; Astroplanets; Bioastronomy; Cosmochemistry; Ecogenomics; Exobiology; Extremophiles; Geomicrobiology; Gravitational biology; Life detection technology; Meteoritics; Planetary geoscience; Planetary protection; Prebiotic chemistry; Space exploration technology; Terraforming
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