作为消化道癌症诊断生物标志物的口腔微生物群:系统综述

S K Aziz Ikbal, Surendra Kumar Yadav, Roopanshi Mehrotra, Tasneem Fatima, Anjusha Sharda, Srashti Gupta
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引用次数: 0

摘要

目的:本文旨在回顾口腔微生物群与消化道癌症(DC)的关系:口腔微生物群是人体内最复杂的生态系统之一。口腔是消化系统的起点,可能是丰富的微生物分类群的来源,这些微生物群进入消化系统后生长、繁殖和定居,形成复杂的微生态环境,导致全身性疾病和胃肠道疾病:共选择了 14 篇文章进行综述。大多数研究为病例对照研究。口腔微生物群与消化道癌症之间既有正相关也有负相关:消化系统癌症可能与独特的口腔微生物特征有关:本系统综述揭示了消化系统癌症风险与口腔微生物群的关系,口腔微生物群可作为生物标志物,以更舒适、可接受和无创的方式早期诊断消化系统癌症。本文引用方式Ikbal SKA, Yadav SK, Mehrotra R, et al. 口腔微生物群作为消化道癌症的诊断生物标志物:系统综述》。J Contemp Dent Pract 2023;24(11):902-911.
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Oral Microbiota as a Diagnostic Biomarker of Digestive Cancer: A Systematic Review.

Aim: This article aimed to review the association of oral microbiota with digestive cancer (DC).

Background: Oral microbiota is one of the most complex ecosystems in our body. The mouth, from which the digestive system starts, may be a source of an abundant taxonomic group of microbiotas that travel to the digestive system followed by growth, reproduction, and settlement, forming a complex microecological environment causing systemic and gastrointestinal (GI) disease.

Review results: A total of 14 articles were chosen for review. Most studies were case-control. Both positive and negative associations were seen between oral microbiome and DC.

Conclusion: Digestive cancer may be associated with distinctive oral microbial character.

Clinical significance: The present systematic review enlightens the risk of digestive carcinoma with oral microbiota that may act as a biomarker for early diagnosis of DC in a more comfortable, acceptable, and noninvasive way. How to cite this article: Ikbal SKA, Yadav SK, Mehrotra R, et al. Oral Microbiota as a Diagnostic Biomarker of Digestive Cancer: A Systematic Review. J Contemp Dent Pract 2023;24(11):902-911.

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来源期刊
Journal of Contemporary Dental Practice
Journal of Contemporary Dental Practice Dentistry-Dentistry (all)
CiteScore
1.80
自引率
0.00%
发文量
174
期刊介绍: The Journal of Contemporary Dental Practice (JCDP), is a peer-reviewed, open access MEDLINE indexed journal. The journal’s full text is available online at http://www.thejcdp.com. The journal allows free access (open access) to its contents. Articles with clinical relevance will be given preference for publication. The Journal publishes original research papers, review articles, rare and novel case reports, and clinical techniques. Manuscripts are invited from all specialties of dentistry i.e., conservative dentistry and endodontics, dentofacial orthopedics and orthodontics, oral medicine and radiology, oral pathology, oral surgery, orodental diseases, pediatric dentistry, implantology, periodontics, clinical aspects of public health dentistry, and prosthodontics.
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