{"title":"揭示麻疹传播动态:非线性发病率随机模型的启示","authors":"Zhenfeng Shi, Daqing Jiang","doi":"10.1111/sapm.12670","DOIUrl":null,"url":null,"abstract":"<p>In this paper, taking into account the inevitable impact of environmental perturbations on disease transmission, we primarily investigate a stochastic model for measles infection with nonlinear incidence. The transmission rate in this model follows a logarithmic normal distribution influenced by an Ornstein–Uhlenbeck (OU) process. To analyze the dynamic properties of the stochastic model, our first step is to establish the existence and uniqueness of a global solution for the stochastic equations. Next, by constructing appropriate Lyapunov functions and utilizing the ergodicity of the OU process, we establish sufficient conditions for the existence of a stationary distribution, indicating the prevalence of the disease. Furthermore, we provide sufficient conditions for disease elimination. These conditions are derived by considering the interplay between the model parameters and the stochastic dynamics. Finally, we validate the theoretical conclusions through numerical simulations, which allow us to assess the practical implications of the established conditions and observe the dynamics of the stochastic model in action. By combining theoretical analysis and numerical simulations, we gain a comprehensive understanding of the stochastic model's behavior, contributing to the broader understanding of measles transmission dynamics and the development of effective control strategies.</p>","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":null,"pages":null},"PeriodicalIF":4.6000,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unveiling measles transmission dynamics: Insights from a stochastic model with nonlinear incidence\",\"authors\":\"Zhenfeng Shi, Daqing Jiang\",\"doi\":\"10.1111/sapm.12670\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>In this paper, taking into account the inevitable impact of environmental perturbations on disease transmission, we primarily investigate a stochastic model for measles infection with nonlinear incidence. The transmission rate in this model follows a logarithmic normal distribution influenced by an Ornstein–Uhlenbeck (OU) process. To analyze the dynamic properties of the stochastic model, our first step is to establish the existence and uniqueness of a global solution for the stochastic equations. Next, by constructing appropriate Lyapunov functions and utilizing the ergodicity of the OU process, we establish sufficient conditions for the existence of a stationary distribution, indicating the prevalence of the disease. Furthermore, we provide sufficient conditions for disease elimination. These conditions are derived by considering the interplay between the model parameters and the stochastic dynamics. Finally, we validate the theoretical conclusions through numerical simulations, which allow us to assess the practical implications of the established conditions and observe the dynamics of the stochastic model in action. By combining theoretical analysis and numerical simulations, we gain a comprehensive understanding of the stochastic model's behavior, contributing to the broader understanding of measles transmission dynamics and the development of effective control strategies.</p>\",\"PeriodicalId\":2,\"journal\":{\"name\":\"ACS Applied Bio Materials\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-01-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ACS Applied Bio Materials\",\"FirstCategoryId\":\"100\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/sapm.12670\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, BIOMATERIALS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/sapm.12670","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
摘要
考虑到环境扰动对疾病传播不可避免的影响,本文主要研究一种非线性发病率的麻疹感染随机模型。该模型中的传播率受奥恩斯坦-乌伦贝克(Ornstein-Uhlenbeck,OU)过程的影响,服从对数正态分布。为了分析随机模型的动态特性,我们首先要确定随机方程全局解的存在性和唯一性。接下来,通过构建适当的 Lyapunov 函数并利用 OU 过程的遍历性,我们建立了静态分布存在的充分条件,表明了疾病的流行程度。此外,我们还提供了疾病消除的充分条件。这些条件是通过考虑模型参数和随机动力学之间的相互作用而得出的。最后,我们通过数值模拟验证了理论结论,从而评估了既定条件的实际意义,并观察了随机模型的动态变化。通过将理论分析和数值模拟相结合,我们对随机模型的行为有了全面的了解,有助于更广泛地了解麻疹的传播动态和制定有效的控制策略。
Unveiling measles transmission dynamics: Insights from a stochastic model with nonlinear incidence
In this paper, taking into account the inevitable impact of environmental perturbations on disease transmission, we primarily investigate a stochastic model for measles infection with nonlinear incidence. The transmission rate in this model follows a logarithmic normal distribution influenced by an Ornstein–Uhlenbeck (OU) process. To analyze the dynamic properties of the stochastic model, our first step is to establish the existence and uniqueness of a global solution for the stochastic equations. Next, by constructing appropriate Lyapunov functions and utilizing the ergodicity of the OU process, we establish sufficient conditions for the existence of a stationary distribution, indicating the prevalence of the disease. Furthermore, we provide sufficient conditions for disease elimination. These conditions are derived by considering the interplay between the model parameters and the stochastic dynamics. Finally, we validate the theoretical conclusions through numerical simulations, which allow us to assess the practical implications of the established conditions and observe the dynamics of the stochastic model in action. By combining theoretical analysis and numerical simulations, we gain a comprehensive understanding of the stochastic model's behavior, contributing to the broader understanding of measles transmission dynamics and the development of effective control strategies.