猴痘病毒 (MPXV) 感染:综述。

Rosy Kumari, Pooja Arya, Surya Prakash Yadav, Ratish Chandra Mishra, Jaya Parkash Yadav
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摘要

猴痘是一种病毒性疾病;世界卫生组织最近宣布猴痘的爆发为全球紧急事件。印度首次发现猴痘病毒(MPXV)感染者。就在 COVID-19 之后,不同的研究人员背靠背地试图找到解决这一卫生紧急事件的方法。在这篇综述中,我们讨论了印度的疫情现状、传播途径、致病因素、症状、治疗方法以及印度卫生部制定的预防指南。我们发现,猴痘病毒(MPXV)疾病与天花不同,30-40 岁年龄组更容易感染 MPXV。我们还发现,除同性恋、双性恋和荤食者外,无旅行史的正常异性恋男女也会感染。应避免近距离接触老鼠、猴子和猴痘患者。迄今为止,还没有治疗猴痘的药物,但 Tecovirimat 比其他治疗天花等病毒性疾病的药物更有效。因此,我们需要研制一种有效的抗病毒药物,以对付猴痘病毒的致病因子。
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Monkeypox Virus (MPXV) Infection: A Review.

Monkeypox is a viral disease; its outbreak was recently declared a global emergency by the World Health Organization. For the first time, a monkeypox virus (MPXV)-infected patient was found in India. Various researchers back-to-back tried to find the solution to this health emergency just after COVID-19. In this review, we discuss the current outbreak status of India, its transmission, virulence factors, symptoms, treatment, and the preventive guidelines generated by the Indian Health Ministry. We found that monkeypox virus (MPXV) disease is different from smallpox, and the age group between 30-40 years old is more prone to MPXV disease. We also found that, besides homosexuals, gays, bisexuals, and non-vegetarians, it also affects normal straight men and women who have no history of travel. Close contact should be avoided from rats, monkeys and sick people who are affected by monkeypox. To date, there are no monkeypox drugs, but Tecovirimat is more effective than other drugs that are used for other viral diseases like smallpox. Therefore, we need to develop an effective antiviral agent against the virulence factor of MXPV.

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