VENERE 研究：北欧式健走对肥胖或超重糖尿病心血管疾病患者的康复治疗效果

IF 2.5 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS CJC Open Pub Date : 2024-05-01 DOI:10.1016/j.cjco.2024.01.002

Anna Torri MD , Eleonora Volpato PsyD, PhD , Giampiero Merati MD , Martina Milani MD , Anastasia Toccafondi , Damiano Formenti PhD , Francesca La Rosa PhD , Simone Agostini PhD , Cristina Agliardi PhD , Letizia Oreni MSc , Alice Sacco MD , Marta Rescaldani MD , Stefano Lucreziotti MD , Ada Giglio MD , Giulia Ferrante MD , Maristella Barbaro MD , Claudio Montalto MD , Stefano Buratti MD , Nuccia Morici MD, PhD

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摘要

背景北欧式健走（NW）对心血管疾病、2 型糖尿病、肥胖和/或超重患者有多种潜在益处。北欧健走能改善心血管健康，包括运动能力和血压控制。负重行走可增强糖尿病患者的血糖控制和胰岛素敏感性，并有助于控制体重和改善身体结构。方法这项开放标签研究分为 3 个阶段，旨在评估肥胖和/或超重糖尿病并发症患者运动处方的有效性、安全性和依从性。主要目的是评估参与者在接受为期 3 个月的 NW 干预后，与标准康复训练和为期 3 个月的心脏病咨询（对照组）训练相比，在 6 个月和 12 个月的随访期后的 CV 表现。此外，安全性和依从性数据将有助于了解长期运动处方的可行性和可持续性。结论这些研究结果可能会对为这一特殊患者群体制定量身定制的运动计划产生影响，从而达到优化心血管健康结果的目的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The VENERE Study: EffectiVenEss of a Rehabilitation Treatment With Nordic Walking in ObEse or OveRweight Diabetic PatiEnts With Cardiovascular Disease

Background

Nordic walking (NW) has several potential benefits for individuals with cardiovascular (CV) disease, type 2 diabetes, and obesity and/or overweight. NW improves cardiovascular health, including exercise capacity and blood pressure control. NW enhances glycemic control and insulin sensitivity in diabetes, and aids in weight management and body composition improvement. NW offers additional advantages, such as improvement in muscular strength, joint mobility, physical activity levels, and psychological well-being.

Methods

This open-label study with 3 arms will aim to evaluate the efficacy, safety, and adherence to exercise prescription in obese and/or overweight diabetic patients with CV complications. The primary objective will be to assess the CV performance of participants after a 6-month and a 12-month follow-up period, following a 3-month NW intervention, compared with standard rehabilitation, and with cardiological counseling (control group) training lasting 3 months.

Results

The results of the study will provide valuable insights into the comparative effectiveness of a NW intervention vs standard rehabilitation and control group training in improving CV performance in obese and/or overweight diabetic patients with CV complications. Additionally, safety and adherence data will help inform the feasibility and sustainability of the exercise prescription over an extended period.

Conclusions

These findings may have implications for the development of tailored exercise programs for this specific patient population, with the aim of optimizing CV health outcomes.