儿科重症监护室心脏手术术后的不良事件:VIS 评分和 RACHS-1 的贡献。

Ana Beatriz Ramos Wasniewski, Claudia Pires Ricachinevsky, Raíssa Queiroz Rezende, Bruna Tomasi Lorentz, Edinara da Silva Silveira, Viviane Helena Rampon Angeli, Mariana González de Oliveira, Themis Reverbel da Silveira
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摘要

目的评估儿科重症监护室心脏手术术后不良事件的发生情况,并找出可预测此类事件的患者特征:这是一项历史队列研究,研究对象为2019年4月至12月期间在儿科重症监护室进行心脏手术后头7天康复治疗的患者,研究方法为查阅病历。研究回顾了以下内容:人口统计学、临床和实验室特征;患者严重程度评分;选定的不良事件,分为设备相关、手术和非手术:结果:共纳入 238 份医疗记录。110名术后患者(46.2%)至少发生了一起不良事件。不良事件总数为 193 起(81%)。血管导管是最常见的原因,其次是心脏骤停、出血和手术再次探查。在单变量分析中,血管活性-肌力评分(VIS)、先天性心脏病手术风险调整(RACHS-1)评分、年龄、儿科死亡率指数(PIM-2)、心肺旁路和主动脉夹闭持续时间与不良事件显著相关。在多变量分析中,VIS≥20(OR 2.90;P = 0.004)和RACHS-1≥3(OR 2.11;P = 0.019)是重要的预测因素,而年龄和延迟胸骨闭合仅显示出显著性趋势。根据VIS和RACHS-1预测不良事件发生率的曲线下面积为0.73(95%CI 0.66 - 0.79):结论:儿童心脏手术后经常发生不良事件,尤其是与器械有关的不良事件。同时使用 VIS 和 RACHS-1 可以很好地预测该儿童样本中不良事件的发生率。
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Adverse events in the postoperative period of cardiac surgery in a pediatric intensive care unit: the contribution of the VIS score and the RACHS-1.

Objective: To evaluate the occurrence of adverse events in the postoperative period of cardiac surgery in a pediatric intensive care unit and to find any patient characteristics that can predict such events.

Methods: This was a historical cohort study of patients recovering in the pediatric intensive care unit for the first 7 days after cardiac surgery between April and December 2019, by reviewing the medical records. The following were reviewed: demographic, clinical, and laboratory characteristics; patient severity scores; and selected adverse events, grouped into device-related, surgical, and nonsurgical.

Results: A total of 238 medical records were included. At least one adverse event occurred in 110 postoperative patients (46.2%). The total number of adverse events was 193 (81%). Vascular catheters were the most common cause, followed by cardiac arrest, bleeding, and surgical reexploration. In the univariate analysis, the vasoactive-inotropic score (VIS), Risk Adjustment in Congenital Heart Surgery (RACHS-1) score, age, Pediatric Index of Mortality (PIM-2), cardiopulmonary bypass and aortic clamping duration were significantly associated with adverse events. In the multivariate analysis, VIS ≥ 20 (OR 2.90; p = 0.004) and RACHS-1 ≥ 3 (OR 2.11; p = 0.019) were significant predictors, while age and delayed sternal closure showed only trends toward significance. To predict the occurrence of adverse events from VIS and RACHS-1, the area under the curve was 0.73 (95%CI 0.66 - 0.79).

Conclusion: Adverse events were quite frequent in children after cardiac surgery, especially those related to devices. The VIS and RACHS-1, used together, predicted the occurrence of adverse events well in this pediatric sample.

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