中国西安室外空气污染物与慢性阻塞性肺病急性加重风险之间的关系

IF 2.9 4区 环境科学与生态学 Q3 ENVIRONMENTAL SCIENCES Air Quality Atmosphere and Health Pub Date : 2024-01-25 DOI:10.1007/s11869-024-01513-6
Xinping Fan, Xueyan Jie, Fan Zou, Dan Wang, Hongju Da, Hongxin Li, Hongyan Zhao, Jin He, Jianghao Liu, Yiyi Lu, Yun Liu
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引用次数: 0

摘要

室外空气污染物与慢性阻塞性肺疾病(AECOPD)急性加重之间的关系一直备受关注。西安具有特殊的盆地地形、气象条件和发达的工业。这些都使得西安的室外空气污染十分严重。因此,我们希望评估中国西安室外空气污染物与 AECOPD 之间的关系。我们从 8 家三级甲等大型综合医院收集了 2018 年每天的 AECOPD 住院和门诊量。从西安市环境保护局和西安市气象局获取了2018年1月1日至12月31日西安市污染物和气象条件数据。数据分析采用了斯皮尔曼秩相关、线性回归和广义加性模型。室外空气污染物(PM10、PM2.5、二氧化硫、二氧化氮和一氧化碳)增加了AECOPD的发病风险。空气污染物对 AECOPD 患者的影响具有滞后效应。PM10、PM2.5、CO 和 NO2 与女性慢性阻塞性肺病患者的急性加重有关。PM10、PM2.5、一氧化碳、二氧化硫和二氧化氮与老年慢性阻塞性肺病患者(70 < 年龄≤ 80 岁)的急性加重有关。CO 与嗜酸性粒细胞绝对计数≥ 300/μL 的慢性阻塞性肺病患者的急性加重有关。PM10与嗜酸性粒细胞绝对计数为100/μL的慢性阻塞性肺病患者的急性加重有关。在西安市,PM10、PM2.5、二氧化硫、二氧化氮和一氧化碳的暴露与慢性阻塞性肺病急性发作的医院就诊率呈显著正相关。各种空气污染物与不同类型的 AECOPD 患者有不同的关系。O3与AECOPD之间的关系仍有待进一步探讨。
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Association between outdoor air pollutants and risk of acute exacerbation of chronic obstructive pulmonary disease in Xi’an, China

Attention has been paid to the association between outdoor air pollutants and acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Xi’an has special basin topography and meteorological conditions as well as developed industries. All these make the outdoor air pollution in Xi 'an serious. Thus, we wish to assess the association between outdoor air pollutants and AECOPD in Xi’an, China. Daily AECOPD inpatient and outpatient visits in 2018 were collected from the eight first-class large general hospitals at grade 3. Data on pollutants and weather conditions in Xi 'an from January 1 to December 31, 2018 were accessed from Xi 'an Environmental Protection Bureau and Xi 'an Meteorological Bureau. Spearman rank correlation, linear regression, and generalized additive models were used for data analysis. Outdoor air pollutants (PM10, PM2.5, SO2, NO2, and CO) increase the risk of AECOPD. The impact of air pollutants on AECOPD patients has a hysteresis effect. PM10, PM2.5, CO, and NO2 are associated with acute exacerbation in female COPD patients. PM10, PM2.5, CO, SO2, and NO2 are associated with acute exacerbation in old COPD patients (70 < age ≤ 80 years old). CO is associated with acute exacerbation in COPD Patients with eosinophils absolute count ≥ 300/μL. PM10 is associated with acute exacerbation in COPD patients with eosinophils absolute count < 100/μL. Exposure to PM10, PM2.5, SO2, NO2, and CO is positively associated significantly with hospital visits for AECOPD in Xi’an. Various air pollutants have different associations with different types of AECOPD patients. The relationship between O3 and AECOPD still needs to be further explored.

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来源期刊
Air Quality Atmosphere and Health
Air Quality Atmosphere and Health ENVIRONMENTAL SCIENCES-
CiteScore
8.80
自引率
2.00%
发文量
146
审稿时长
>12 weeks
期刊介绍: Air Quality, Atmosphere, and Health is a multidisciplinary journal which, by its very name, illustrates the broad range of work it publishes and which focuses on atmospheric consequences of human activities and their implications for human and ecological health. It offers research papers, critical literature reviews and commentaries, as well as special issues devoted to topical subjects or themes. International in scope, the journal presents papers that inform and stimulate a global readership, as the topic addressed are global in their import. Consequently, we do not encourage submission of papers involving local data that relate to local problems. Unless they demonstrate wide applicability, these are better submitted to national or regional journals. Air Quality, Atmosphere & Health addresses such topics as acid precipitation; airborne particulate matter; air quality monitoring and management; exposure assessment; risk assessment; indoor air quality; atmospheric chemistry; atmospheric modeling and prediction; air pollution climatology; climate change and air quality; air pollution measurement; atmospheric impact assessment; forest-fire emissions; atmospheric science; greenhouse gases; health and ecological effects; clean air technology; regional and global change and satellite measurements. This journal benefits a diverse audience of researchers, public health officials and policy makers addressing problems that call for solutions based in evidence from atmospheric and exposure assessment scientists, epidemiologists, and risk assessors. Publication in the journal affords the opportunity to reach beyond defined disciplinary niches to this broader readership.
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