Niosomes:定向给药系统

Shrikrushna M. Khambalkar, Aishwarya D. Ghuge, Swati P. Deshmukh, Krushna P. Jadhav, Roshan V. Jaiswal, Amit A. Khune
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引用次数: 0

摘要

Niosomes 是一种由非离子表面活性剂构成的多层膜囊泡结构。Niosomes 在给药系统中充当药物载体。Niosomes 可保护药物免受宿主生物环境的影响,从而延迟药物的清除时间,提高了封装药物分子的治疗效果。在这篇综述文章中,我们将重点讨论药物 Niosomes,它是药物输送系统的一种常规方法。与脂质体相比,niosomes 无毒的优势使其更适合药物输送系统。它们能够同时封装亲水性和亲油性药物,这也增加了目前对它们的需求。因此,本文更多关注的是在当前情况下作为一种新方法使用的 Niosomes 的开发方法。
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Niosomes: A targeted drug delivery system
Niosomes are the multilamellar vesicles structure of non-ionic surfactant. Niosomes act as a drug carrier in drug delivery system. Niosomes improved the therapeutic performance of encapsulated drug molecules by protecting the drug from host biological environments resulting in their delayed clearance. In this present review article, we concentrate on the drug Niosomes which is a normal approach for drug delivery system. The niosomes have become the area of interest in the drug delivery system their advantage one liposomes in the field of drug delivery system for being non-toxic makes them more suitable for drug delivery system. Their ability to encapsulate both hydrophilic, lipophilic drugs simultaneously has increased its demand in the present scenario. Niosomes are vesicles made up of non-ionic surfactant, which are biodegradable, nontoxic, more stable and inexpensive and have ability to substitute liposomes but they also flexibility in the route of administration Thus, in the present articles more focus is made on the development method of niosomes which is used as a novel approach in present scenario So, Niosomes as a drug carrier is of greater Importance in the pharmaceutical field
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