用于伤口愈合的无机纳米材料复合水凝胶敷料

Ying Yang, Pingfei Wang, Guiju Zhang, Shan He, Baocai Xu
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摘要

伤口管理在很大程度上依赖于伤口敷料的重要贡献,这就强调了找到一种理想敷料的重要性,这种敷料能够满足伤口愈合过程中的复杂要求,并具有多种功能。一种前景广阔的策略是将多种材料和疗法结合起来,创造出多功能伤口敷料。基于纳米材料的纳米复合水凝胶敷料结合了纳米材料和水凝胶在伤口治疗中的优势,可以显著改善它们各自的性能并弥补它们的不足。近年来,各种结构多样、功能协同的纳米复合伤口敷料相继问世,在伤口管理应用中取得了理想的效果。本综述首先讨论了水凝胶作为伤口敷料的多种功能、优势和局限性。此外,还阐述了无机纳米材料在伤口愈合中的应用。此外,我们还重点总结和分析了用于伤口愈合的纳米复合水凝胶敷料,其中包含各种无机纳米材料,包括金属、金属氧化物、金属硫化物、碳基纳米材料和硅基纳米颗粒。最后,展望了纳米复合水凝胶伤口敷料的前景,为伤口管理方面的进一步研究提供了启示。
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Inorganic-Nanomaterial-Composited Hydrogel Dressings for Wound Healing
Wound management heavily relies on the vital contribution of wound dressings, emphasizing the significance of finding an ideal dressing that can fulfill the intricate requirements of the wound healing process with multiple functions. A promising strategy is combining several materials and therapies to create multifunctional wound dressings. Nanocomposite hydrogel dressings based on nanomaterials, combining the advantages of nanomaterials and hydrogels in wound treatment, can significantly improve their respective performance and compensate for their shortcomings. A variety of nanocomposite wound dressings with diverse structures and synergistic functions have been developed in recent years, achieving ideal results in wound management applications. In this review, the multiple functions, advantages, and limitations of hydrogels as wound dressings are first discussed. Additionally, the application of inorganic nanomaterials in wound healing is also elaborated on. Furthermore, we focused on summarizing and analyzing nanocomposite hydrogel dressings for wound healing, which contain various inorganic nanomaterials, including metals, metal oxides, metal sulfides, carbon-based nanomaterials, and silicon-based nanoparticles. Finally, prospects for nanocomposite hydrogel wound dressings are envisaged, providing insights for further research in wound management.
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