详细回顾免疫疗法,特别强调杂交瘤技术

Arunkumar Ramjibhai Vaghela, Tejas H. Ganatra
{"title":"详细回顾免疫疗法,特别强调杂交瘤技术","authors":"Arunkumar Ramjibhai Vaghela, Tejas H. Ganatra","doi":"10.25259/ajbps_13_2023","DOIUrl":null,"url":null,"abstract":"The paper offers a thorough analysis of immunotherapeutics with a focus on hybridomas. It describes how focused and precise treatments for a variety of illnesses, such as cancer, autoimmune disorders, and infectious diseases, have been made possible by immunotherapeutics, which are based on antibody and hybridoma technology. The main therapeutics produced by this method are monoclonal antibodies (mAbs). The article describes the hybridoma technology process, in which a heterogeneous population of cells that produce unique mAbs are created by combining immortalized myeloma cells with B lymphocytes. To isolate and create drug formulations, the hybridoma cells that produce the desired antibodies are chosen and grown in large numbers. In the article, successful uses of immunotherapeutics based on antibody and hybridoma technology are highlighted. Hybridoma technology used in treatment of autoimmune conditions, viral infections and cancer. The potential of mAbs to increase the range of available treatments is also covered. The page also describes the distinction between monoclonal and polyclonal antibodies, how they are made, and the different uses of hybridoma technology in research, diagnostics, therapy, vaccine development, and fundamental immunology investigations. The importance of immunotherapeutics based on antibody and hybridoma technologies in revolutionizing the treatment environment and creating new opportunities for customized and targeted therapies is emphasized as it draws to a close.","PeriodicalId":93408,"journal":{"name":"American journal of biopharmacy and pharmaceutical sciences","volume":"11 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A detailed review of immunotherapeutics with a special emphasis on hybridoma technology\",\"authors\":\"Arunkumar Ramjibhai Vaghela, Tejas H. Ganatra\",\"doi\":\"10.25259/ajbps_13_2023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The paper offers a thorough analysis of immunotherapeutics with a focus on hybridomas. It describes how focused and precise treatments for a variety of illnesses, such as cancer, autoimmune disorders, and infectious diseases, have been made possible by immunotherapeutics, which are based on antibody and hybridoma technology. The main therapeutics produced by this method are monoclonal antibodies (mAbs). The article describes the hybridoma technology process, in which a heterogeneous population of cells that produce unique mAbs are created by combining immortalized myeloma cells with B lymphocytes. To isolate and create drug formulations, the hybridoma cells that produce the desired antibodies are chosen and grown in large numbers. In the article, successful uses of immunotherapeutics based on antibody and hybridoma technology are highlighted. Hybridoma technology used in treatment of autoimmune conditions, viral infections and cancer. The potential of mAbs to increase the range of available treatments is also covered. The page also describes the distinction between monoclonal and polyclonal antibodies, how they are made, and the different uses of hybridoma technology in research, diagnostics, therapy, vaccine development, and fundamental immunology investigations. The importance of immunotherapeutics based on antibody and hybridoma technologies in revolutionizing the treatment environment and creating new opportunities for customized and targeted therapies is emphasized as it draws to a close.\",\"PeriodicalId\":93408,\"journal\":{\"name\":\"American journal of biopharmacy and pharmaceutical sciences\",\"volume\":\"11 7\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of biopharmacy and pharmaceutical sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25259/ajbps_13_2023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of biopharmacy and pharmaceutical sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25259/ajbps_13_2023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

本文以杂交瘤为重点,对免疫疗法进行了深入分析。它描述了免疫疗法是如何利用抗体和杂交瘤技术对癌症、自身免疫性疾病和传染病等多种疾病进行集中和精确治疗的。这种方法生产的主要疗法是单克隆抗体(mAbs)。文章介绍了杂交瘤技术的过程,即通过将永生化骨髓瘤细胞与 B 淋巴细胞结合,产生能产生独特 mAbs 的异质细胞群。为了分离和制造药物制剂,需要选择能产生所需抗体的杂交瘤细胞并进行大量培养。文章重点介绍了基于抗体和杂交瘤技术的免疫疗法的成功应用。杂交瘤技术用于治疗自身免疫性疾病、病毒感染和癌症。文章还介绍了 mAbs 在扩大可用治疗范围方面的潜力。该页还介绍了单克隆抗体和多克隆抗体的区别、制造方法,以及杂交瘤技术在研究、诊断、治疗、疫苗开发和基础免疫学调查中的不同用途。本章最后强调了基于抗体和杂交瘤技术的免疫疗法在彻底改变治疗环境以及为定制和靶向疗法创造新机遇方面的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
A detailed review of immunotherapeutics with a special emphasis on hybridoma technology
The paper offers a thorough analysis of immunotherapeutics with a focus on hybridomas. It describes how focused and precise treatments for a variety of illnesses, such as cancer, autoimmune disorders, and infectious diseases, have been made possible by immunotherapeutics, which are based on antibody and hybridoma technology. The main therapeutics produced by this method are monoclonal antibodies (mAbs). The article describes the hybridoma technology process, in which a heterogeneous population of cells that produce unique mAbs are created by combining immortalized myeloma cells with B lymphocytes. To isolate and create drug formulations, the hybridoma cells that produce the desired antibodies are chosen and grown in large numbers. In the article, successful uses of immunotherapeutics based on antibody and hybridoma technology are highlighted. Hybridoma technology used in treatment of autoimmune conditions, viral infections and cancer. The potential of mAbs to increase the range of available treatments is also covered. The page also describes the distinction between monoclonal and polyclonal antibodies, how they are made, and the different uses of hybridoma technology in research, diagnostics, therapy, vaccine development, and fundamental immunology investigations. The importance of immunotherapeutics based on antibody and hybridoma technologies in revolutionizing the treatment environment and creating new opportunities for customized and targeted therapies is emphasized as it draws to a close.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Emerging contaminants at trace levels of pesticides perturbs biomolecules in different organs in mice: Role of peroxisome proliferator-activated receptor-alpha A detailed review of immunotherapeutics with a special emphasis on hybridoma technology Angelman syndrome: A genetic challenge for physical and learning disabilities Molecular and qualitative characterization of compatibility between valacyclovir hydrochloride and excipients as raw materials for the development of solid oral dosage formulation Complete Freund’s adjuvant-induced arthritis in rats: Anti-inflammatory and antioxidant properties of Allanblackia gabonensis (guttiferae) aqueous extract
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1